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Dihydroberberine

Catalog No. T8189 CAS 483-15-8

Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces HSP90 expression and its interaction with hERG.

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Dihydroberberine, CAS 483-15-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 41.00
5 mg	In stock	$ 97.00
10 mg	In stock	$ 172.00
25 mg	In stock	$ 322.00
50 mg	In stock	$ 478.00
100 mg	In stock	$ 688.00
1 mL * 10 mM (in DMSO)	In stock	$ 123.00

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Purity: 93.77%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interaction with hERG.
Source	Natural Products > Papaveraceae > Corydalis

Molecular Weight	337.4
Formula	C20H19NO4
CAS No.	483-15-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 3.37 mg/mL (10 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Yu D, et al. Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells. PLoS One. 2017 Aug 1;12(8):e0181823.

Related compound libraries

This product is contained In the following compound libraries：

Cytokine Inhibitor Library Angiogenesis related Compound Library JAK-STAT Compound Library Anti-Pancreatic Cancer Compound Library Tyrosine Kinase Inhibitor Library Bioactive Compounds Library Max Bioactive Compound Library Anti-Tumor Natural Product Library Anti-Fibrosis Compound Library Ion Channel Inhibitor Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Dihydroberberine 483-15-8 Angiogenesis Cytoskeletal Signaling JAK/STAT signaling Membrane transporter/Ion channel Metabolism Tyrosine Kinase/Adaptors HER Potassium Channel HSP inhibit KcsA Inhibitor Heat shock proteins inhibitor

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