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Search Results for " interleukin-5 "

Targets

16

Compounds

3

Natural Products

39

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T9962 Mepolizumab SB 240563 IL Receptor
Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis.
T3133 YM-90709 YM90709,YM 90709 IL Receptor , Interleukin
YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.
T9537 N'-Nitro-D-arginine N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid Others
N'-Nitro-D-arginine (N'-Nitro-D-arginine) is a Building Block.
T7606 Guanosine 5'-diphosphate disodium salt 5'-GDP-Na2 Endogenous Metabolite
Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway.
T14367 AZ1495 IRAK , CDK , Haspin Kinase
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffu...
T10497 Benralizumab BIW-8405,MEDI-563 Apoptosis , IL Receptor , Interleukin
Benralizumab (MEDI-563) is a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα). It enhances antibody-dependent cell-mediated cytotoxicity, leading to a rapid depletion of eosinophils. Benralizumab i...
T12706 Reslizumab Sch 55700 IL Receptor
Reslizumab is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma.
T80577 Varokibart
Varokibart (TEV-53275) is a human IgG4λ antibody that targets interleukin-5 (IL-5) [1].
T70107 Olcorolimus
Olcorolimus inhibits single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mRNA expression for interleukin (IL)-4 and IL-5
T82060 Interleukin-6 fragment (human)
Interleukin-6 Fragment (human) is a pleiotropic cytokine originating from both lymphocytes and non-lymphocytes, encoded by a gene on human chromosome 7 spanning roughly 5 kilobases. This fragment shows promise for use in...
T4186 AC-264613 AC264613 Protease-activated Receptor
AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613(AC264613) suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macropha...
T72120 Guanosine 5'-diphosphate sodium GDP sodium
Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel and serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin i...
T36668 Geranylgeranoic Acid
Geranylgeranoic acid (GGA) is an isoprenoid that has been found inS. chinensisand has anticancer activity.1It induces apoptosis in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes, but not...
T37554 Oleyl Anilide
AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransfera...
T37604 ITK inhibitor
Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine recept...
T38106 JC-171
JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages with an IC50 of 8.45 μM[1].
Cat No. Product Name Synonyms Targets
T6S1538 Neochlorogenic acid trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid TNF , NF-κB , COX , Antibacterial , Interleukin
Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
TN1291 7,3',4'-Tri-O-methylluteolin 5-Hydroxy-3',4',7-trimethoxyflavone TNF , COX , Interleukin
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC value of 19.0 ug/ml
T7210 Guanosine 5'-diphosphate GDP Endogenous Metabolite
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02554 IL-5 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
IL-5 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 14.5 kDa and the accession number is P04401.
TMPY-05576 IL-5 Protein, Human, Recombinant (His) Human HEK293 Cells
IL-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is P05113.
TMPY-03915 IL-5 Protein, Human, Recombinant Human E. coli
IL-5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.1 kDa and the accession number is P05113.
TMPY-01871 IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) Human HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-02087 IL-24 Protein, Human, Recombinant (His) Human HEK293 Cells
IL-24 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.5 kDa and the accession number is A0A7R8C2Y5.
TMPY-01371 IL-17RA Protein, Human, Recombinant (His) Human HEK293 Cells
IL-17RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is Q96F46-1.
TMPY-02739 IL-5 Protein, Canine, Recombinant (His) Canine Baculovirus Insect Cells
IL-5 Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 14.54 kDa and the accession number is Q95J76.
TMPY-05070 IL-5 Protein, Cynomolgus, Recombinant (His) Cynomolgus Baculovirus Insect Cells
IL-5 Protein, Cynomolgus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 14.6 kDa.
TMPY-05536 IL-5 Protein, Human, Recombinant (mFc) Human HEK293 Cells
IL-5 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 39.5 kDa and the accession number is P05113.
TMPY-03522 IL-5R alpha/CD125 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
IL-5R alpha/CD125 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 36.87 kDa and the accession number is P21183.
TMPK-00772 IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k...
TMPK-00771 IL-5 Protein, Mouse, Recombinant (His & Avi) Mouse HEK293 Cells
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k...
TMPK-00021 IL-5 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k...
TMPJ-00020 IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cel...
TMPJ-00267 IL-5R alpha/CD125 Protein, Human, Recombinant (aa 21-335, His) Human HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant (aa 21-335, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 45-60 KDa and the accession number is Q01344.
TMPJ-00266 IL-5R alpha/CD125 Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-85 KDa and the accession number is Q01344.
TMPY-06391 IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated Human HEK293 Cells
IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 36.71 kDa and the accession number is Q96F46-1.
TMPY-05430 IL-17RA Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-17RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.2 kDa and the accession number is Q96F46-1.
TMPY-05177 IL-24 Protein, Human, Recombinant (mFc) Human HEK293 Cells
IL-24 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 44.6 kDa and the accession number is A0A7R8C2Y5.
TMPY-05120 IL-17RA Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
IL-17RA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.9 kDa and the accession number is Q96F46-1.
TMPY-05119 IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated Human HEK293 Cells
IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 61.6 kDa and the accession number is Q96F46-1.
TMPY-06390 IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293 Cells
IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 61.99 kDa and the accession number is Q96F46-1.
TMPJ-01210 IL-33 Protein, Mouse, Recombinant Mouse E. coli
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi...
TMPY-06981 IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) Human E. coli
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPK-00269 IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Interleukin5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5. ...
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His) Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5.
TMPK-00268 IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Interleukin5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5. ...
TMPK-00242 IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated Human HEK293 Cells
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 sub...
TMPJ-01234 IL-36 gamma Protein, Mouse, Recombinant Mouse E. coli
Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in b...
TMPY-03496 EBAG9 Protein, Human, Recombinant (His) Human E. coli
RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen ...
TMPH-02156 SOCS1 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Through ...
TMPJ-00789 Flagellin Protein, Salmonella Typhimurium, Recombinant Salmonella typhimurium E. coli
Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin...
TMPJ-00854 ETS1 Protein, Human, Recombinant (His) Human E. coli
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ...
TMPY-05498 SR-BI/SCARB1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5.
TMPY-05387 SLAMF7 Protein, Human, Recombinant (hFc) Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-05547 SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5.
TMPY-04318 GRIK2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPK-01363 SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01357 SIRP alpha V5 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
IL-5 Protein, Mouse, Recombinant (His)
TMPY-02554
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-5 Protein, Human, Recombinant (His)
TMPY-05576
Species: Human
Expression System: HEK293 Cells
IL-5 Protein, Human, Recombinant
TMPY-03915
Species: Human
Expression System: E. coli
IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)
TMPY-01871
Species: Human
Expression System: HEK293 Cells
IL-24 Protein, Human, Recombinant (His)
TMPY-02087
Species: Human
Expression System: HEK293 Cells
IL-17RA Protein, Human, Recombinant (His)
TMPY-01371
Species: Human
Expression System: HEK293 Cells
IL-5 Protein, Canine, Recombinant (His)
TMPY-02739
Species: Canine
Expression System: Baculovirus Insect Cells
IL-5 Protein, Cynomolgus, Recombinant (His)
TMPY-05070
Species: Cynomolgus
Expression System: Baculovirus Insect Cells
IL-5 Protein, Human, Recombinant (mFc)
TMPY-05536
Species: Human
Expression System: HEK293 Cells
IL-5R alpha/CD125 Protein, Mouse, Recombinant (His)
TMPY-03522
Species: Mouse
Expression System: Baculovirus Insect Cells
IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPK-00772
Species: Mouse
Expression System: HEK293 Cells
IL-5 Protein, Mouse, Recombinant (His & Avi)
TMPK-00771
Species: Mouse
Expression System: HEK293 Cells
IL-5 Protein, Human, Recombinant (His & Avi)
TMPK-00021
Species: Human
Expression System: HEK293 Cells
IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00020
Species: Human
Expression System: HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant (aa 21-335, His)
TMPJ-00267
Species: Human
Expression System: HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant (hFc)
TMPJ-00266
Species: Human
Expression System: HEK293 Cells
IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated
TMPY-06391
Species: Human
Expression System: HEK293 Cells
IL-17RA Protein, Human, Recombinant (hFc)
TMPY-05430
Species: Human
Expression System: HEK293 Cells
IL-24 Protein, Human, Recombinant (mFc)
TMPY-05177
Species: Human
Expression System: HEK293 Cells
IL-17RA Protein, Human, Recombinant (His), Biotinylated
TMPY-05120
Species: Human
Expression System: HEK293 Cells
IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated
TMPY-05119
Species: Human
Expression System: HEK293 Cells
IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06390
Species: Human
Expression System: HEK293 Cells
IL-33 Protein, Mouse, Recombinant
TMPJ-01210
Species: Mouse
Expression System: E. coli
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
TMPY-06981
Species: Human
Expression System: E. coli
IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00269
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 1-529, His)
TMPY-05308
Species: Human
Expression System: HEK293 Cells
IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi)
TMPK-00268
Species: Human
Expression System: HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated
TMPK-00242
Species: Human
Expression System: HEK293 Cells
IL-36 gamma Protein, Mouse, Recombinant
TMPJ-01234
Species: Mouse
Expression System: E. coli
EBAG9 Protein, Human, Recombinant (His)
TMPY-03496
Species: Human
Expression System: E. coli
SOCS1 Protein, Human, Recombinant (His)
TMPH-02156
Species: Human
Expression System: P. pastoris (Yeast)
Flagellin Protein, Salmonella Typhimurium, Recombinant
TMPJ-00789
Species: Salmonella typhimurium
Expression System: E. coli
ETS1 Protein, Human, Recombinant (His)
TMPJ-00854
Species: Human
Expression System: E. coli
SR-BI/SCARB1 Protein, Human, Recombinant (hFc)
TMPY-05498
Species: Human
Expression System: HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc)
TMPY-05387
Species: Human
Expression System: HEK293 Cells
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05547
Species: Human
Expression System: HEK293 Cells
GRIK2 Protein, Human, Recombinant (hFc)
TMPY-04318
Species: Human
Expression System: HEK293 Cells
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-01363
Species: Human
Expression System: HEK293 Cells
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
TMPK-01357
Species: Human
Expression System: HEK293 Cells
TargetMol