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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8206 | Cycleanine | Others | |
Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities. | |||
TN3848 | Dihydrobaicalein | PLK | |
Dihydrobaicalein is a natural product from Scutellaria baicalensis, a PLK1 inhibitor (IC50:6.3 μM).Dihydrobaicalein inhibits VRK2 and PLK2. | |||
T4S1718 | Punicalin | HBV , HIV Protease | |
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM). | |||
TN1427 | Baicalin methyl ester | Anti-infection | |
Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT). | |||
T2858 | Baicalein | 5,6,7-Trihydroxyflavone | Ferroptosis , Influenza Virus , ROS , Xanthine Oxidase |
Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor. | |||
T3116 | Atorvastatin hemicalcium salt | Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,Sortis | Ferroptosis , HMG-CoA Reductase , Autophagy |
Atorvastatin hemicalcium salt (Atorvastatin Calcium), an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication. | |||
T69984 | Ticalopride | 5-HT Receptor | |
Ticalopride is a 5-HT3 receptor agonist used in the treatment of digestive disorders, orofacial disorders, otorhinolaryngologic disorders, and may be used in the study of bulimia nervosa, gastroesophageal reflux, and irr... | |||
TQ0200 | Paricalcitol | ||
Paricalcitol is a vitamin D receptor agonist. It is used for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure. | |||
T3921 | Punicalagin | SARS-CoV , HBV | |
Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumula... | |||
T0380 | Bicalutamide | ICI-176334 | Androgen Receptor , Autophagy |
Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. | |||
T2775 | Baicalin | Baicalein 7-O-β-D-glucuronide | NF-κB , HIV Protease , GABA Receptor , Autophagy |
Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV properties. | |||
T3551 | D-Pantothenic acid hemicalcium salt | D-Pantothenic Acid Calcium,Calpanate,Calcium D-pantothenate,Vitamin B5 calcium salt,Calcium pantothenate,Calcium D-Panthotenate | Apoptosis , Endogenous Metabolite |
D-Pantothenic acid hemicalcium salt (Calcium pantothenate), a kind of water soluble vitamin, can reduce the patulin content of the apple juice. | |||
T29067L | Upacicalcet HCl | Upacicalcet HCl(1333218-50-0 Free base) | CaSR |
Upacicalcet HCl is an intravesical calcium mimetic that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on calcium-sensitive receptors in parathyroid cell membranes, thereby lowering PTH levels ... | |||
TP2048L | α-helical CRF 9-41 acetate | α-helical CRF 9-41 acetate(90880-23-2 Free base) | CRFR |
α-helical CRF 9-41 acetate is a competitive antagonist of CRF2 (KB = 100 nM) and a partial agonist of CRF1 (EC50 = 140 nM). | |||
T4200 | Sacubitril hemicalcium salt | AHU-377 (hemicalcium salt),AHU377 calcium salt | Neprilysin |
Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug ... | |||
T29067 | Upacicalcet | PLS-240,SK-1403,AJT-240 | Calcium Channel |
Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-s... | |||
T39444 | Upacicalcet sodium | ||
Upacicalcet (sodium) is an intravenous calcimimetic agent that acts directly on parathyroid cell membrane calcium-sensing receptors to suppress excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH le... | |||
T83665 | α-Helical CRF (9-41) TFA | α-Helical Corticotropin-Releasing Factor (9-41) | |
α-Helical CRF (9-41) is a synthetic peptide antagonist that targets corticotropin-releasing factor (CRF), effectively inhibiting CRF-induced adrenocorticotropic hormone (ACTH) release both in vitro, with isolated rat ant... | |||
T69385 | Baicalein monohydrate | ||
Baicalein monohydrate is an inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. | |||
T75272 | Paricalcitol-d | ||
Paricalcitol-d6, a deuterium-labeled version of Paricalcitol, serves as a therapeutic agent for preventing and treating secondary hyperparathyroidism (excessive secretion of parathyroid hormone) linked to chronic renal f... |