Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.Upacicalcet is an orthosteric modulator of calcium-sensitive receptors and prevents adenine-induced secondary vascular calcification and bone disease in a rat model of adenine-induced secondary hyperparathyroidism.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 110.00 | |
5 mg | In stock | $ 270.00 | |
10 mg | In stock | $ 400.00 | |
25 mg | In stock | $ 668.00 | |
50 mg | In stock | $ 949.00 | |
100 mg | In stock | $ 1,290.00 | |
500 mg | In stock | $ 2,580.00 |
Description | Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.Upacicalcet is an orthosteric modulator of calcium-sensitive receptors and prevents adenine-induced secondary vascular calcification and bone disease in a rat model of adenine-induced secondary hyperparathyroidism. |
Synonyms | PLS-240, SK-1403, AJT-240 |
Molecular Weight | 351.76 |
Formula | C11H14ClN3O6S |
CAS No. | 1333218-50-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Upacicalcet 1333218-50-0 Membrane transporter/Ion channel Metabolism Calcium Channel PLS-240 AJT240 SK1403 PLS 240 SK-1403 SK 1403 AJT 240 AJT-240 PLS240 inhibitor inhibit