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Baicalin methyl ester

Baicalin methyl ester
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Baicalin methyl ester

Catalog No. TN1427Cas No. 82475-03-4
Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).
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Pack SizePriceAvailabilityQuantity
1 mg$50In Stock
5 mg$138In Stock
10 mg$198In Stock
25 mg$347In Stock
1 mL x 10 mM (in DMSO)$161In Stock
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Product Introduction

Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).
In vitro
One hundred-ninety flavonoids and 75 alkaloids were studied for their inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT) by using (rA) n-p(dT) <12-18> or (rC) n-p(dG) <12-18> as a template-primer. Of the flavonoids tested, 6-hydroxyluteolin (50), pedalitin (52), 6-hydroxykaempferol (109) and quercetagetin (129), were the most potent inhibitors with IC50?:10 μM. Five other flavonoids, baicalein (19), Baicalin methyl ester (23), scutellarein (33), myricetin (126) and gossypetin (130), gave IC50 between 35 and 200 μM. The kinetic studies on 50, 126 and 130 gave the inhibitory constants ki of 10, 94 and 90 μM, respectively, with respect to the substrate and 5, 200 and 100 μM, respectively, with respect to the template-primer. Structurally different alkaloids such as isoquinoline, indol, steroidal, quinolizidine, pyrrolizidine, pyridine and imidazole alkaloids were also investigated for the activity and berberine type alkaloids were shown to have a strong inhibitory activity.
Chemical Properties
Molecular Weight460.39
Cas No.82475-03-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 45 mg/mL (97.74 mM)
Solution Preparation Table
1 mM2.1721 mL10.8604 mL21.7207 mL108.6036 mL
5 mM0.4344 mL2.1721 mL4.3441 mL21.7207 mL
10 mM0.2172 mL1.0860 mL2.1721 mL10.8604 mL
20 mM0.1086 mL0.5430 mL1.0860 mL5.4302 mL
50 mM0.0434 mL0.2172 mL0.4344 mL2.1721 mL


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