hrv — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6516	Golgicide A		Others , Virus Protease
	Golgicide A is a potent and rapidly reversible GBF1 inhibitor.		Others , Virus Protease
T5779	MOSLOFLAVONE		IL Receptor , Virus Protease , TNF , Antibacterial
	MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.		IL Receptor , Virus Protease , TNF , Antibacterial
T2432	PD 169316		Virus Protease , p38 MAPK , Autophagy
	PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.		Virus Protease , p38 MAPK , Autophagy
T1750	Pirodavir	R77975	Virus Protease , Antiviral
	Pirodavir (R77975) (R 77975), the prototype of broad-spectrum anti-picornavirus compounds, is a potent human rhinovirus (HRV) capsid-binding inhibitor.		Virus Protease , Antiviral
T4061	LY2334737		Nucleoside Antimetabolite/Analog , Others , Virus Protease
	LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.		Nucleoside Antimetabolite/Analog , Others , Virus Protease
T18928	Brilliant Black BN	E 151	Others , Virus Protease
	Brilliant Black BN (E 151) is an azo dye and a food colorant. It is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A.		Others , Virus Protease
T8205	Norwogonin	5,7,8-Trihydroxyflavone	Virus Protease
	Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).		Virus Protease
T1670	Lanatoside C	Cedilanid,Ceglunate,Isolanid	ATPase , Virus Protease , Autophagy
	Lanatoside C (Ceglunate) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Lanatoside C can be used orally or by the intrav...		ATPase , Virus Protease , Autophagy
T5S2360	Corydaline	Corydalin,(+)-Corydaline	P450 , Virus Protease , Opioid Receptor , AChE
	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...		P450 , Virus Protease , Opioid Receptor , AChE
T4492	Pocapavir	SCH-48973,V-073	Virus Protease , Antiviral
	Pocapavir (SCH-48973) is an investigational enterovirus (EV) capsid inhibitor.		Virus Protease , Antiviral
T4536	Pleconaril	VP 63843,Win 63843,Picovir	Virus Protease , Antiviral
	Pleconaril (VP 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM).		Virus Protease , Antiviral
T3345	Hederasaponin B	Eleutheroside M,Hederacoside B	Others , Virus Protease
	Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.		Others , Virus Protease
TN2111	Prunin	Naringenin 7-0-glucoside	Phosphatase , Anti-infection , Virus Protease
	Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can...		Phosphatase , Anti-infection , Virus Protease
T0188	Fluticasone (propionate)	CCI-187881,Fluticasone propionate	Glucocorticoid Receptor , Virus Protease , Estrogen/progestogen Receptor , Phospholipase , Endogenous Metabolite
	Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist.
T8498	EIDD-1931	Beta-d-N4-hydroxycytidine	Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
	EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndr...		Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
T16809	Rupintrivir	AG-7088,AG7088,Rupintrivirvr	Virus Protease , Antiviral
	Rupintrivirvr (AG7088) is a selective rhinovirus (HRV) 3C cysteine protease mimetic peptide inhibitor with antiviral and immunomodulatory activities.Rupintrivirvr inhibits the replication of EV71 and EV-D68, and may be u...		Virus Protease , Antiviral
T28550	Ro 09-0410	Ro-09-0410,Ro 09 0410
	Ro 09-0410 is an antivirus agent. Ro 09-0410 binds to human rhinovirus type 2 (HRV-2) and inactivates the virus.
T80470	Citrullinated LL-37 2cit
	Citrullinated LL-37 2cit, a modified version of the LL-37 peptide, attenuates the antiviral efficacy of LL-37 against Human Rhinovirus (HRV) at a concentration of 10 μg/mL and diminishes its antibacterial properties. Fur...
T80473	Citrullinated LL-37 3cit		Influenza Virus
	Citrullinated LL-37 3cit is a host defense peptide with potent immunomodulatory and antimicrobial properties, demonstrating direct antiviral activity against human rhinoviruses (HRV) [1].		Influenza Virus
T0104	Umifenovir hydrochloride	Arbidol hydrochloride,Arbidol HCl	SARS-CoV , Influenza Virus
	Umifenovir hydrochloride (Arbidol HCl) , an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host cell membrane.		SARS-CoV , Influenza Virus