eos — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22440	TP-353	EOS-61973	CDK
	TP-353 (EOS-61973) is a CDK7 inhibitor.		CDK
T4667	EOS-62062
	Pesampator (PF-04958242) is a potent, highly selective positive allosteric modulator of the AMPA receptor, also known as an AMPA potentiator, demonstrating an EC50 of 310 nM and a Ki of 170 nM [1].
T37461	EOS (d18:1/32:1/18:2)
	EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an ω-hydroxy very long-chain ceramide (C28-36) esterified to the essential fatty acid linoleic acid . The consecutive regio- and ...
T4307	PF-06840003	EOS200271,PF 06840003	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T82901	Belrestotug	GSK4428859A,EOS884448,EOS-448
	Belrestotug (EOS-448), an antagonistic anti-TIGIT (VSIG9, VSTM3) antibody of the human immunoglobulin G1 kappa (hIgG1 kappa) class, exhibits antineoplastic activity [1].
T9901A-008	Volociximab	Eos 200-4,M200	Integrin
	Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.		Integrin
T69647	UCM-05194
	UCM-05194 is a potent Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1). UCM-05194 Shows Efficacy in Neuropathic Pain Amelioration. UCM-05194 stands out as the most potent and selective LPA1 receptor agonist de...
T17159	Treosulfan	NSC 39069,Treosulphan	DNA Alkylator/Crosslinker , DNA Alkylation
	Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.		DNA Alkylator/Crosslinker , DNA Alkylation
TN6789	Neosalvianen		Others
	Neosalvianen was isolated from Salvia miltiorrhiza.		Others
T6102	2'-acetylacteoside		Antioxidant , Reductase
	2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Acetylacteoside shows antiproliferative effects on aortic smoo...		Antioxidant , Reductase
T3892	Isoacteoside	Isoverbascoside	NF-κB
	Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p...		NF-κB
T38364	MeOSuc-AAPV-AMC	MeOSuc-Ala-Ala-Pro-Val-AMC
	MeOSuc-AAPV-AMC (MeOSuc-Ala-Ala-Pro-Val-AMC) is a tetrapeptide that is a fluorescent substrate for human leukocyte and porcine pancreatic elastase.
TN3543	Bruceoside A		Others
	Bruceoside A is a bitter wood glycoside that can be isolated from opuntia and has anticancer and tumor activity and can be used with the study of leukemia.		Others
T16684	Puromycin aminonucleoside	NSC 3056	Apoptosis , Proteasome , Aminopeptidase , Antibacterial , Antibiotic
	Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.
T1612	Neostigmine methyl sulfate	Normastigmin,Hodostin,Syntostigmin	AChR , AChE
	Neostigmine methyl sulfate (Syntostigmin) is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier, used in the treatment of myasthenia gravis.		AChR , AChE
T3800	Typhaneoside	Aervitrin	Others , Autophagy
	Typhaneoside (Aervitrin) is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.		Others , Autophagy
T20446	Creosol		Endogenous Metabolite
	Creosol is an agent of Antioxidant and Antibacterial.		Endogenous Metabolite
T3824	Jaceosidin		Apoptosis , BCL , COX , UGT
	Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...		Apoptosis , BCL , COX , UGT
TN7094	Coreoside B		Antibacterial
	Coreoside B is isolated from coreoside and showed weak antimicrobial activity against S. aureus and B. anthracis.		Antibacterial
TN1975	Neosmitilbin	Neoastilbin	Others
	Neosmitilbin (Neoastilbin) may have antioxidant and anti-inflammatory activities, it shows potent inhibition of lens aldose reductase.		Others