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Bruceoside A

Catalog No. TN3543 CAS 63306-30-9

Bruceoside A is a bitter wood glycoside that can be isolated from opuntia and has anticancer and tumor activity and can be used with the study of leukemia.

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Bruceoside A, CAS 63306-30-9

Pack Size	Availability	Price/USD
1 mg	In stock	$ 139.00
5 mg	In stock	$ 345.00
10 mg	In stock	$ 513.00
25 mg	In stock	$ 833.00
50 mg	In stock	$ 1,215.00

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Purity: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Bruceoside A is a bitter wood glycoside that can be isolated from opuntia and has anticancer and tumor activity and can be used with the study of leukemia.
In vitro	Similar inhibitory effects on P-388 cell oxidative phosphorylation were found in vitro with brusatol, bruceoside A, and bruceantin[1].
In vivo	Bruceoside A can undergo transformation into the potent anticancer component brusatol in vivo, rather than being directly metabolized into its deglycosylated form, bruceosin[2].

Molecular Weight	682.67
Formula	C32H42O16
CAS No.	63306-30-9

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (146.48 mM), Sonication is recommended.

References and Literature

1. Eigebaly SA, et al. Antitumor agents. XXXV: Effects of brusatol, bruceoside A, and bruceantin on P-388 lymphocytic leukemia cell respiration. J Pharm Sci. 1979 Jul;68(7):887-90. 2. Yuan Xu, et al. Pharmacokinetic study on bruceoside A revealed the potential role of quassinoid glycosides for the anticancer properties of Fructus Bruceae. J Pharm Biomed Anal. 2019 Jun 5;170:264-272.

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Bruceoside A 63306-30-9 inhibitor inhibit

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