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Search Result

Search Results for " bh "

62

Compounds

2

Natural Products

13

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T26792 BH-IAA
BH-IAA is a potent auxin antagonist.
T1493 BH3I-1 BHI1 BCL , E1/E2/E3 Enzyme
BH3I-1 (BHI1) is a Bcl-2 antagonist.
TP1724L PUMA BH3 acetate PUMA BH3 acetate(PUMA BH3 Free base) BCL
PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of 26 nM.
TP1808 Bak BH3
This peptide, generated from the BH3 domain of Bak (Flu-BakBH3), has been shown to have high-affinity binding to a surface pocket of the Bcl-XL protein that is required for its death antagonist function.
TP1724 PUMA BH3
PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochond...
TP1836 BMf-BH3
BMf-BH3 belongs to the Bcl-2 apoptosis mediator family. This peptide belongs to the Bcl-2 apoptosis mediator family. Bmf is a key player in histone deacetylase (HDAC) inhibition, which alters the balance between deacetyl...
TP1611 Bim BH3, Peptide IV
This Bim peptide belongs to the pro-apoptotic group of the Bcl-2 family of proteins.
TP1712 PUMA BH3 (TFA)
PUMA BH3 (TFA) is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.
T26789 BH3I-2' BH3I2',BH3I 2'
BH3I-2' is a cell-permeable BH3 mimetic. BH3I-2' induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the in...
T40379 Bax BH3 peptide (55-74), wild type Bax BH3 peptide (55-74), wild type
Bax BH3 peptide (55-74), wild type is a 20-amino acid peptide (Bax 1) known for its ability to induce apoptosis in various cell line models.
TP1718 Bim BH3, Peptide IV TFA (721885-31-0 free base) Bim BH3, Peptide IV TFA
Bim BH3, Peptide IV TFA is a 26-site residue of BH3 protein Bim, belonging to the pro-apoptotic group of bcl-2 protein family.
T6348 NVP-BHG712 Raf , Bcr-Abl , Src , Ephrin Receptor
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respecti...
T4450 GIBH-130 IL Receptor , TNF , Interleukin
GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.
T0113 Mebhydrolin napadisylate Incidal,Diazolin,Mebhydroline 1,5-naphthalenedisulfonate salt,Omeril,Diazoline 5-HT Receptor , AChR , Histamine Receptor
Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.
T19487 NVP-BHG712 isomer Ephrin Receptor
NVP-BHG712 isomer shows conserved non-bonded binding to EPHA2 and EPHB4.
T61428 4-PQBH Others
4-PQBH is a potent Nur77-binding agent with antitumour activity.4-PQBH inhibits xenograft tumours through Nur77-mediated endoplasmic stress and autophagy by broadly inducing cysteoaspartase-independent cytoplasmic vacuol...
T4176 Rac-BHFF (R,S)-BHFF GABA Receptor
rac-BHFF ((R,S)-BHFF) is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). It exhibits anxiolytic activity in vivo an...
T25210 CBHcy Transferase
CBHcy is a dual-substrate analogue, a specific BHMT inhibitor that causes betaine-homocysteine S-methyltransferase (BHMT) to adopt the same conformation as the ternary complex, potentially inducing the development of cys...
T5364 TBHQ tert-Butylhydroquinone Apoptosis , ERK , Others , Ferroptosis , Nrf2 , Autophagy
TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.
T7085 Mebhydrolin Mebhydroline Histamine Receptor
Mebhydrolin (Mebhydroline) is a specific histamine H1 receptor antagonist.
T67882 (2R,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol Others
(2R,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder.
T66453 Fmoc PNA-G-(Bhoc)-OH
Fmoc PNA-G-(Bhoc)-OH is a useful organic compound for research related to life sciences and the catalog number is T66453.
T80029 Bak BH3 (72-87), TAMRA-labeled
Bak BH3 (72-87), TAMRA-labeled, is a bioactive peptide.
T80227 Noxa A BH3
Noxa A BH3, a bioactive peptide, encompasses the BH3 domain of the Noxa protein.
T83114 Angiopep-Bim BH3 hydrochloride
Angiopep-Bim BH3 hydrochloride, a peptode that penetrates the blood-brain barrier (BBB), may serve as a tool to study the permeability of central nervous system (CNS) therapeutics [1].
T80231 Bik BH3
Bik BH3, a biologically active peptide derived from the BH3 domain of BIK, exhibits specific functions pertinent to its origin.
T83870 BHD
BHD, a reversible male contraceptive agent, effectively induces spermatogenic cell apoptosis and causes abnormalities in seminiferous tubules in vivo at doses of 100 and 500 mg/kg. Additionally, it disrupts the blood-tes...
T21719 CBHA
m-Carboxycinnamic acid bishydroxamide, an effective HDAC inhibitor, shows ID50 values of 10 nM for HDAC1 and 70 nM for HDAC3 in vitro, demonstrating its potent activity. Additionally, it promotes apoptosis and inhibits t...
T14553 BHPI Others
BHPI is a potent ERα inhibitor that blocks nuclear estrogen–ERα-regulated gene expression effectively. It triggers sustained ERα-dependent activation of the endoplasmic reticulum (EnR) stress sensor, notably the unfolded...
T19574 TBHBA 2,4,6-Tribromo-3-hydroxybenzoic acid Others
TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a brominated aromatic compound. It has been found to inhibit the enzyme cyclooxygenase-2 (COX-2), the enzyme lipoxygenase (LOX), the enzyme 5-lipoxygenase (5-LOX), the enzy...
T70182 NVP-BHS345
NVP-BHS345 is a dual inhibitor of TORC1 and TORC2.
T12121 MtbHU-IN-1 Others
MtbHU-IN-1 is a Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU)inhibitor(binding to WT MtbHU with a Kd of 98 nM).
T80224 Bid BH3 (80-99)
Bid BH3 (80-99) is a biologically active peptide known as a pro-apoptotic member of the 'BH3-only' (BOPS) subset within the BCL-2 protein family, pivotal in apoptosis regulation. It notably interacts with Bcl-2, Bax, and...
T80038 Bim BH3
Bim BH3 is a bioactive peptide that belongs to the pro-apoptotic Bcl-2 family of proteins.
T80223 Bad BH3 (mouse)
Bad BH3 (mouse) is a bioactive peptide derived from the BH3 domain (a death domain) of Bad, encompassing amino acid residues 140 to 165, and functions by binding to bcl-2.
T82889 BHQ-1 NHS
BHQ-1 NHS is a compound that is directly labeled with fluorescently labeled nucleotide.
T80226 R8 Bid BH3
r8 Bid BH3, a biologically active peptide, is a pro-apoptotic member of the "BH3-only" subset within the BCL-2 family proteins, pivotal in regulating apoptosis. This compound exhibits lethality towards Bcl-2-expressing h...
T80221 TAT-BH4 (Bcl-xL) Apoptosis
TAT-BH4 (Bcl-xL), primarily localized at the mitochondria, inhibits apoptotic cell death. This compound comprises an N-terminal eosin-labeled cysteine and the protein transduction domain of the HIV TAT protein (amino aci...
T75980 PUMA BH3 TFA
PUMA BH3 (TFA), a peptide from the BH3 domain of the p53 upregulated modulator of apoptosis (PUMA), directly activates Bak with a dissociation constant (Kd) of 26 nM [1].
T31218 DBHDA
DBHDA is a reagent to convert a Cys into a Dha moiety by reacting with a C-terminal Cys residue and thus allowing the use of recombinant Ubl G76C mutants to prepare probes.
T37889 BHBM
BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal ...
T70380 ZBH-1205
ZBH-1205 is a novel camptothecin derivative, revealing potent antitumor activities mainly through cell apoptosis pathway, being more effective than cpt-11 and sn38 at inhibiting topoismerase-1
T26790 Bharangin
Bharangin is a inhibitor of penicillinase enzyme in E coli.
T125136 Bhilawanol A
Bhilawanol A is a useful organic compound for research related to life sciences. The catalog number is T125136 and the CAS number is 2764-91-2.
T66452 Fmoc-PNA-C(Bhoc)-OH
Fmoc-PNA-C(Bhoc)-OH is a useful organic compound for research related to life sciences and the catalog number is T66452.
T25566 KBH-A42 KBH-A-42,KBHA42,KBH-A 42,KBH A 42
KBH-A42 is an inhibitor of histone deacetylase.
T26791 BHF-177
BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.
T60643 FabH-IN-1
FabH-IN-1 (compound 3f) is effective against gram-positive and gram-negative as well as a good antioxidant. FabH-IN-1 is an inhibitor of bacterial 3-oxoacyl-[acyl-carrier-protein] synthase 3 (FabH) enzyme which is a broa...
T26516 ABH Hydrochloride 6-borono-L-norleucine,ABH HCl
ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses.
T80229 Noxa B BH3
Noxa B BH3, a biologically active peptide encompassing the BH3 domain of the Noxa protein, displays targeted biological activity.

Compounds

BH-IAA
T26792
Synonym:
Target:
BH3I-1
T1493
Synonym: BHI1
Target: BCL, E1/E2/E3 Enzyme
PUMA BH3 acetate
TP1724L
Synonym: PUMA BH3 acetate(PUMA BH3 Free base)
Target: BCL
Bak BH3
TP1808
Synonym:
Target:
PUMA BH3
TP1724
Synonym:
Target:
BMf-BH3
TP1836
Synonym:
Target:
Bim BH3, Peptide IV
TP1611
Synonym:
Target:
PUMA BH3 (TFA)
TP1712
Synonym:
Target:
BH3I-2'
T26789
Synonym: BH3I2',BH3I 2'
Target:
Bax BH3 peptide (55-74), wild type
T40379
Synonym: Bax BH3 peptide (55-74), wild type
Target:
Bim BH3, Peptide IV TFA (721885-31-0 free base)
TP1718
Synonym: Bim BH3, Peptide IV TFA
Target:
NVP-BHG712
T6348
Synonym:
Target: Raf, Bcr-Abl, Src, Ephrin Receptor
GIBH-130
T4450
Synonym:
Target: IL Receptor, TNF, Interleukin
Mebhydrolin napadisylate
T0113
Synonym: Incidal,Diazolin,Mebhydroline 1,5-naphthalenedisulfonate salt,Omeril,Diazoline
Target: 5-HT Receptor, AChR, Histamine Receptor
NVP-BHG712 isomer
T19487
Synonym:
Target: Ephrin Receptor
4-PQBH
T61428
Synonym:
Target: Others
rac-BHFF
T4176
Synonym: (R,S)-BHFF
Target: GABA Receptor
CBHcy
T25210
Synonym:
Target: Transferase
TBHQ
T5364
Synonym: tert-Butylhydroquinone
Target: Apoptosis, ERK, Others, Ferroptosis, Nrf2, Autophagy
Mebhydrolin
T7085
Synonym: Mebhydroline
Target: Histamine Receptor
(2R,3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1H,2H,3H,4H,6H,7H,11bH-pyrido[2,1-a]isoquinolin-2-ol
T67882
Synonym:
Target: Others
Fmoc PNA-G-(Bhoc)-OH
T66453
Synonym:
Target:
Bak BH3 (72-87), TAMRA-labeled
T80029
Synonym:
Target:
Noxa A BH3
T80227
Synonym:
Target:
Angiopep-Bim BH3 hydrochloride
T83114
Synonym:
Target:
Bik BH3
T80231
Synonym:
Target:
BHD
T83870
Synonym:
Target:
CBHA
T21719
Synonym:
Target:
BHPI
T14553
Synonym:
Target: Others
TBHBA
T19574
Synonym: 2,4,6-Tribromo-3-hydroxybenzoic acid
Target: Others
NVP-BHS345
T70182
Synonym:
Target:
MtbHU-IN-1
T12121
Synonym:
Target: Others
Bid BH3 (80-99)
T80224
Synonym:
Target:
Bim BH3
T80038
Synonym:
Target:
Bad BH3 (mouse)
T80223
Synonym:
Target:
BHQ-1 NHS
T82889
Synonym:
Target:
r8 Bid BH3
T80226
Synonym:
Target:
TAT-BH4 (Bcl-xL)
T80221
Synonym:
Target: Apoptosis
PUMA BH3 TFA
T75980
Synonym:
Target:
DBHDA
T31218
Synonym:
Target:
BHBM
T37889
Synonym:
Target:
ZBH-1205
T70380
Synonym:
Target:
Bharangin
T26790
Synonym:
Target:
Bhilawanol A
T125136
Synonym:
Target:
Fmoc-PNA-C(Bhoc)-OH
T66452
Synonym:
Target:
KBH-A42
T25566
Synonym: KBH-A-42,KBHA42,KBH-A 42,KBH A 42
Target:
BHF-177
T26791
Synonym:
Target:
FabH-IN-1
T60643
Synonym:
Target:
ABH Hydrochloride
T26516
Synonym: 6-borono-L-norleucine,ABH HCl
Target:
Noxa B BH3
T80229
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T17056 Tetrahydrobiopterin Sapropterin,BH4,(Rac)-Sapropterin NOS , Endogenous Metabolite
Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercho...
T83554 (4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one
(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone featuring a complex bicyclic structure [1].

Natural Products

Tetrahydrobiopterin
T17056
Synonym: Sapropterin,BH4,(Rac)-Sapropterin
Target: NOS, Endogenous Metabolite
(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one
T83554
Synonym:
Target:

Recombinant Proteins

Species：
Human (9)
Bacillus halodurans (1)
EBV (1)
Mouse (1)
Mycobacterium tuberculosis (1)
Expression System：
E. coli (11)
Baculovirus-Insect Cells (2)
Tag：
His (6)
N-terminal 6xHis-SUMO-tagged (2)
N-6His (1)
N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged (1)
N-terminal 10xHis-tagged (1)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (1)
N-terminal 6xHis-tagged (1)
Cat No. Product Name Species Expression System
TMPY-01865 BLMH Protein, Mouse, Recombinant (His) Mouse E. coli
The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide...
TMPY-01460 ABHD4 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain...
TMPH-01899 ALKBH5 Protein, Human, Recombinant (His) Human E. coli
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Can also deme...
TMPH-03012 HBHA Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) Mycobacterium tuberculosis E. coli
Required for extrapulmonary dissemination. Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells.
TMPJ-00516 OBhFc1 Protein, Human, Recombinant (His) Human E. coli
CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA ...
TMPY-02978 ABHD14B Protein, Human, Recombinant (His) Human E. coli
ABHD14B belongs to the AB hydrolase superfamily, ABHD14 family. It can be detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal mu...
TMPH-00846 ABHD5 Protein, Human, Recombinant (His & SUMO) Human E. coli
Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfert of an acyl group on a lysophosphatidic acid. Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-ly...
TMPY-03414 ABHD10 Protein, Human, Recombinant (aa 53-306, His) Human Baculovirus-Insect Cells
Mycophenolic acid (MPA), the active metabolite of the immunosuppressant mycophenolate mofetil (MMF), is primarily metabolized by glucuronidation to a phenolic glucuronide (MPAG) and an acyl glucuronide (AcMPAG). It is...
TMPH-00158 BH0637 Protein, Bacillus halodurans, Recombinant (His & Myc & SUMO) Bacillus halodurans E. coli
BH0637 Protein, Bacillus halodurans, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-01929 ABHD18 Protein, Human, Recombinant (His & SUMO) Human E. coli
ABHD18 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00535 Epstein-Barr virus (strain B95-8) BHRF1 Protein (His) EBV E. coli
Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic pro...
TMPY-02700 BCL2 Protein, Human, Recombinant (His) Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPY-03452 PTS Protein, Human, Recombinant (His) Human E. coli
PTS(6-pyruvoyltetrahydropterin synthase) belongs to the PTPS family. It catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesi...
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