asa — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0005	Aspirin	Acetylsalicylate,Acetylsalicylic Acid,ASA	Mitophagy , Virus Protease , COX , Autophagy
	Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...		Mitophagy , Virus Protease , COX , Autophagy
T0646	5-Aminosalicylic Acid	Mesalazine,5-ASA,Mesalamine	NF-κB , Lipoxygenase , COX , Glutathione Peroxidase , Endogenous Metabolite , PAK , PPAR
	5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.
T6273	Vadimezan	DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404	Influenza Virus , VDA , STING , IFNAR
	Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without aff...		Influenza Virus , VDA , STING , IFNAR
T18595	Dasatinib carbaldehyde	PROTAC ABL binding moiety 4,BMS-354825 carbaldehyde	Others , Ligands for Target Protein for PROTAC
	Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER [1].		Others , Ligands for Target Protein for PROTAC
T2322	Fimasartan	BR-A-657,Kanarb	Apoptosis , RAAS
	Fimasartan (BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic hydrochlorothiazide has show...		Apoptosis , RAAS
TN6931	Anemarrhenasaponin Ia	(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]oxy}-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxan	Others
	Anemarrhenasaponin Ia ((2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]...		Others
T12361	Parcetasal	MR-897	Others
	Parcetasal (MR-897) is a non-steroidal anti-inflammatory agent that can be used in pain relief studies.		Others
T3345	Hederasaponin B	Eleutheroside M,Hederacoside B	Others , Virus Protease
	Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.		Others , Virus Protease
T3765	L-asarinin	(-)-Episesamin	Others
	L-asarinin ((-)-Episesamin) reduces peripheral blood concentration of IL-12 and inhibits the expression of CXCR3 and TLR4, which means Asarinin may have a role on the TLR4 pathway and produce prolongation of allograft he...		Others
T11680	Isoasatone A		P450
	Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity.		P450
T2733	Sarsasapogenin	Parigenin,Sarsagenin	Apoptosis , NF-κB , Endogenous Metabolite
	Sarsasapogenin (Parigenin) is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. It is named after sarsaparilla (Smilax sp.), a family of climbing plants found in subtropical regions. It was one o...		Apoptosis , NF-κB , Endogenous Metabolite
T6816	DASA-58		PKM
	DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.		PKM
TN2232	Soyasaponin Ab		NOS , NF-κB , COX
	Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab.		NOS , NF-κB , COX
T4S0675	Polygalasaponin V		Others
	Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk m...		Others
TN2043	Pasakbumin B	13-alpha-(21)-Epoxyeurycomanone	Others
	Pasakbumin B (13-alpha-(21)-Epoxyeurycomanone) is a bioactive compound from Eurycoma longifolia Jack.		Others
T2S0690	Ecliptasaponin A	Echinocystic acid-3-o-glucoside	Others
	1. Ecliptasaponin A (Echinocystic acid-3-o-glucoside) has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-...		Others
T6090	Belnacasan	VX-765	Caspase
	Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.		Caspase
T3510	Olumacostat Glasaretil		Acetyl-CoA Carboxylase
	Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.		Acetyl-CoA Carboxylase
T1448L	Dasatinib monohydrate	BMS-354825 Monohydrate	Apoptosis , Bcr-Abl , Src , c-Kit , Ephrin Receptor , Autophagy
	Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activit...
T15716	Lasalocid sodium	Ionophore X-537A sodium,Antibiotic X-537A sodium,Lasalocid-A sodium	Antibacterial , Antibiotic , Autophagy
	Lasalocid sodium (Lasalocid-A sodium) is a cationic ionophore antibiotic obtained from Streptomyces lasaliensis that, among other effects, dissociates the calcium fluxes in muscle fibers. Lasalocid sodium is used as a co...		Antibacterial , Antibiotic , Autophagy