voltage-dependent — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1765	Erastin		Ferroptosis , VDAC
	Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations. The product...		Ferroptosis , VDAC
T3572	NSC 15364	1,3-Bis(4-aminophenyl)urea,NSC15364	Apoptosis , Others , VDAC
	NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.		Apoptosis , Others , VDAC
T18975	DIDS sodium salt	MDL101114ZA	VDAC , ABC
	DIDS sodium salt (MDL101114ZA) is a dual inhibitor of ABCA1 and VDAC1.		VDAC , ABC
T2141	Mecamylamine hydrochloride	Inversine,Mevasin	AChR
	Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.		AChR
T3377	L-Phenylalanine	(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine	Calcium Channel , Endogenous Metabolite , iGluR
	L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.		Calcium Channel , Endogenous Metabolite , iGluR
T0825	Ebselen	SPI-1005,PZ-51,CCG-39161	Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease
	Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b...
T16887	Sipatrigine	619C89,BW 619C89	Calcium Channel , Sodium Channel
	Sipatrigine is a glutamate release inhibitor and voltage-dependent sodium channel.		Calcium Channel , Sodium Channel
T20341	DNDS		CFTR
	DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).		CFTR
T13428	(5R)-BW-4030W92		Sodium Channel
	(5R)-BW-4030W92 is the R-type of BW-4030W92, the active enantiomer. (5R)-BW-4030W92 is an orally available, non-selective, voltage-dependent and use-dependent sodium channel antagonist for the study of neurological disor...		Sodium Channel
T17227	Vernakalant Hydrochloride	RSD1235 hydrochloride	Potassium Channel , Sodium Channel
	Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.		Potassium Channel , Sodium Channel
TN1121	Evocarpine		Apoptosis , cAMP , Anti-infection , Calcium Channel , Antibacterial
	Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
T21263	Amlodipine maleate	Amlodipine (+-)-form maleate,Amvaz	Calcium Channel
	Amlodipine maleate (Amvaz) is an orally active dihydropyridine calcium channel blocker that inhibits calcium inward flow by blocking voltage-dependent L-type calcium channels.Amlodipine maleate is used in the study of hy...		Calcium Channel
T0596	Phenylhydantoin	5-Phenylhydantoin	Others
	5-Phenylhydantoin (5-Phenylhydantoin) is a metabolite of Mephenytoin. 5-Phenylhydantoin has been shown to bind to voltage-dependent sodium channels (NVSC) and has anti-epileptic properties.		Others
T30188L	Atagabalin HCl	PD-0200390 HCl,Atagabalin HCl(223445-75-8 Free base）	Calcium Channel
	Atagabalin HCl is a novel voltage-dependent calcium channel (VDCC) α2δ subunit (1 and 2) ligand that affects slow-wave sleep and can be used to treat insomnia.		Calcium Channel
T7502L	PF 05089771	PF-05089771,PF05089771	Sodium Channel
	PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that is depolarization and concentration-dependent.		Sodium Channel
T26778	Besipirdine	HP 749 free base,P-867493,P867493,HP 749,HP749,P 867493	Sodium Channel , Adrenergic Receptor
	Besipirdine (HP 749 free base) is a non-receptor-dependent cholinomimetic compound with alpha-adrenergic and cardiovascular activities.Besipirdine inhibits voltage-dependent sodium-potassium channels and inhibits biogeni...		Sodium Channel , Adrenergic Receptor
T26778L	Besipirdine hydrochloride	HP 749 hydrochloride,Besipirdine hydrochloride（119257-34-0 Free base)	Adrenergic Receptor
	Besipirdine hydrochloride is a non-receptor-dependent cholinomimetic compound with alpha-adrenergic and cardiovascular activities.Besipirdine hydrochloride inhibits voltage-dependent sodium-potassium channels and inhibit...		Adrenergic Receptor
T13287	VBIT-4		VDAC
	VBIT-4 is a voltage-dependent anion channel 1 (VDAC1) oligomerization inhibitor (Kd: 17 μM). VBIT-4 can be used for therapeutic purposes in apoptosis-associated disorders (such as neurodegenerative and cardiovascular dis...		VDAC
T0030	Bupivacaine hydrochloride	Vivacaine,Bupivacaine HCl	Sodium Channel
	Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the vol...		Sodium Channel
T68060	Elgodipine
	Elgodipine significantly reduced the incidence and severity of exercise-induced angina pectoris systemically and was able to inhibit vascular smooth muscle proliferation through a mechanism independent of the expression ...