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DIDS sodium salt
🥰Excellent
Catalog No. T18975Cas No. 67483-13-0
Alias MDL101114ZA
DIDS sodium salt (MDL101114ZA) is a dual inhibitor of the proteins ABCA1 and VDAC1.
DIDS sodium salt
🥰Excellent
Purity: 99.34%
Catalog No. T18975Alias MDL101114ZACas No. 67483-13-0
DIDS sodium salt (MDL101114ZA) is a dual inhibitor of the proteins ABCA1 and VDAC1.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | 31 € | In Stock | |
| 25 mg | 48 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 28 € | In Stock |
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Purity:99.34%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | DIDS sodium salt (MDL101114ZA) is a dual inhibitor of the proteins ABCA1 and VDAC1. |
| In vitro | DIDS (<400 μM) has no evident cytotoxic effect on cell viability Pre-treatment with DIDS at the concentration of 100 and 200 μM result in a prevented effect on ALA-SDT-induced cell death, while dose at 50 μM has no inhibition effect. Pre-treatment with DIDS (100 μM) clearly inhibit caspase-3 and caspase-9 activation [2]. |
| Alias | MDL101114ZA |
| Molecular Weight | 498.5 |
| Formula | C16H8N2Na2O6S4 |
| Cas No. | 67483-13-0 |
| Smiles | O.[Na+].[Na+].[O-]S(=O)(=O)c1cc(ccc1C=Cc1ccc(cc1S([O-])(=O)=O)N=C=S)N=C=S |
| Relative Density. | 1.54g/cm3 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (90.27 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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