vasodilatory — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7656	Apelin-13
	Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ...
T0075	Nicorandil	SG-75	Potassium Channel
	Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. Firstly, by activating potassium channels, and secondly b...		Potassium Channel
T1410	Torsemide	AC-4464,JDL-464,Torasemide	Na-K-Cl cotransporter
	Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and h...		Na-K-Cl cotransporter
T3518	GSK269962A	GSK269962B,GSK 269962,GSK269962A HCl	ROCK , S6 Kinase
	GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.		ROCK , S6 Kinase
T7437	3-(3-Hydroxyphenyl)propionic Acid	m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid	Others , Endogenous Metabolite
	3-(3-Hydroxyphenyl)propionic Acid (m-Hydroxyphenylpropionic acid) is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bone osteoclastic resorptive activity.		Others , Endogenous Metabolite
T15471	Hepronicate	Megrin	Others
	Hepronicate（Megrin） is a small molecule compound with hypolipidemic and vasodilatory activity.		Others
T27323	FK-453	FK453,FK 453	Adenosine Receptor
	FK-453 is a potent antagonist of non-xanthine adenosine A1 receptor with diuretic and renal vasodilatory activity.		Adenosine Receptor
T13684	Equilin	7-Dehydroestrone	Calcium Channel
	Equilin (7-Dehydroestrone) is a neurotrophic estrogenic steroid with vasodilatory activity that increases monocyte-endothelial adhesion through NF-κB signalling.Equilin similarly relaxes mesenteric arterial resistance by...		Calcium Channel
T68083L	Dl-Ibuterol hydrochloride	dl-Ibuterol hydrochloride (53034-85-8 Free base),dl-Ibuterol HCl,Ibuterol HCl	Others
	dl-Ibuterol hydrochloride (Ibuterol HCl) has vasodilatory activity and can be used to study asthma and bronchospasm.		Others
T0853	Adenosine	D-Adenosine,Adenine riboside	Apoptosis , Nucleoside Antimetabolite/Analog , Endogenous Metabolite , Autophagy
	Adenosine (D-Adenosine) is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.
T0370	Pheniramine maleate	Daneral,Inhiston,Trimetose	5-HT Receptor , Histamine Receptor
	Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re...		5-HT Receptor , Histamine Receptor
T14064	8-Bromo-cGMP sodium		Calcium Channel , PKA
	8-Bromo-cGMP sodium is a PKG activator, a membrane-permeable analog of cGMP. 8-Bromo-cGMP sodium has pain-relieving and vasodilatory effects, significantly inhibits Ca2+ macroscopic currents, and inhibits high K+-stimula...		Calcium Channel , PKA
T8135	Minoxidil sulfate	Minoxidil sulphate,U-58838	Potassium Channel
	Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.		Potassium Channel
T1398	Tadalafil	Cialis,IC-351	Apoptosis , PDE
	Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGM...		Apoptosis , PDE
T36033	DETA NONOate	NOC-18,Diethylamine NONOate	NO Synthase
	DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity.DETA NONOate can be used to activate inward currents in neurons, which may accelerate the healing of MRSA-infect...		NO Synthase
T68138	Saterinone		Adrenergic Receptor , PDE
	Saterinone is a potent and selective phosphodiesterase III inhibitor and a potent antagonist of the vascular α-1-adrenoceptor. Saterinone has vasodilatory properties and can be used in the acute treatment of chronic hear...		Adrenergic Receptor , PDE
T1158	Phenoxybenzamine hydrochloride	NCI-c01661,NSC 37448,Phenoxybenzamine HCl	CaMK , Adrenergic Receptor
	Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non...		CaMK , Adrenergic Receptor
T3904	Gomisin J		Calcium Channel , AMPK
	Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK...		Calcium Channel , AMPK
TN1393	(-)-Anonaine		Apoptosis , Antioxidant , Parasite , Antifungal
	(-)-Anonaine can be extracted from several species of Magnoliaceae and Annelidae and has antimalarial, antibacterial, antifungal, antioxidant, anticancer, antidepressant and vasodilatory activities. (-)-Anonaine induces ...		Apoptosis , Antioxidant , Parasite , Antifungal
T3011	2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid	Kynurenine,Dl-Kynurenine,Kynurenin,3-Anthraniloylalanine	Others , Endogenous Metabolite
	2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid (3-Anthraniloylalanine) is a ketone and an amino acid derivative with diverse biological functions, including vasodilatory, immunoregulatory and neuromodulatory activities. 2-...		Others , Endogenous Metabolite