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Torsemide

Catalog No. T1410 CAS 56211-40-6

Synonyms: 托拉塞米, AC-4464, JDL-464, Torasemide

Torsemide is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and has a relatively long half-life.

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Torsemide, CAS 56211-40-6

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	托拉塞米, AC-4464, JDL-464, Torasemide
Molecular Weight	348.42
Formula	C16H20N4O3S
CAS No.	56211-40-6

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Goodfriend TL, et al. Life Sci,1998, 63(3), PL45-50. 2. Peddle GD, et al. J Vet Cardiol,2012, 14(1), 253-259. 3. Hori Y, et al. Am J Vet Res,2007, 68(10), 1058-1063.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Anti-Cardiovascular Disease Compound Library Inhibitor Library Ion Channel Inhibitor Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library FDA-Approved Drug Library Kinase Inhibitor Library Approved Drug Library Anti-Cancer Drug Library

Related Products

Related compounds with same targets

Furosemide sodium Torsemide Azosemide Furosemide

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Torsemide 56211-40-6 离子通道 Na-K-Cl cotransporter vasodilatory disease hepatic renal Inhibitor diuretic anti-aldosterone cirrhosis AC-4464 JDL-464 heart failure inhibit Torasemide inhibitor

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