sensitive — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15385	Glibornuride		Potassium Channel
	Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent.		Potassium Channel
T9014	SKI-178		Apoptosis , S1P Receptor
	SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ...		Apoptosis , S1P Receptor
T9714	Atpenin A5		Potassium Channel
	Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].		Potassium Channel
T4316	ML365		Potassium Channel
	ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3).		Potassium Channel
T0343	Nimodipine	BAY-e 9736	Glucocorticoid Receptor , AhR , Calcium Channel , Autophagy
	Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.		Glucocorticoid Receptor , AhR , Calcium Channel , Autophagy
T1781	GW9508	GW 9508	GPR , Potassium Channel
	GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.		GPR , Potassium Channel
T1198	Tetracaine hydrochloride	Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl	Calcium Channel , Sodium Channel
	Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been use...		Calcium Channel , Sodium Channel
T26795	PXS-4728A	BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl	Monoamine Oxidase
	BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2].		Monoamine Oxidase
T1603	Glipizide	CP 28720,K 4024	Potassium Channel , PPAR , ABC
	Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.		Potassium Channel , PPAR , ABC
T1634	Glibenclamide	Glyburide	Potassium Channel , Mitochondrial Metabolism , CFTR , P-gp , Autophagy
	Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
T1952	MK-2206 dihydrochloride	MK-2206 2HCl	Apoptosis , Akt , Autophagy
	MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor a...		Apoptosis , Akt , Autophagy
T1101	Minocycline hydrochloride	Minocycline HCl	HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
	Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...		HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
T11979	McN5691	RWJ26240	Calcium Channel
	McN5691 is a voltage sensitive calcium channel blocker.		Calcium Channel
T23233L	RETF-4NA acetate	RETF-4NA acetate（1160928-63-1 free base）	Others
	RETF-4NA acetate is a sensitive, specific substrate for chymotrypsin.		Others
T14999	CORM-401		Others
	CORM-401 is an oxidant-sensitive CO-releasing molecule. It can be used in oxidative stress-mediated pathologies and the research of inflammatory.		Others
T74235	DHAPC
	DHAPC is a phospholipid that is very sensitive to oxidation [1] .
TQ0150	Levcromakalim	(-)-Cromakalim,BRL 38227	Potassium Channel
	Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.		Potassium Channel
T10566	BMS-191095		Potassium Channel
	BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.		Potassium Channel
T20968	CyPPA		Potassium Channel , Dopamine Receptor
	CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolarization.		Potassium Channel , Dopamine Receptor
T18974	DiBAC4(3)		Others
	DiBAC4(3) is a voltage-sensitive fluorescent dye (λem=505 nm, λex=490 nm).		Others