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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15385 | Glibornuride | Potassium Channel | |
Glibornuride is an ATP-sensitive K+ channels (KATP channel) blocker ( pKi: 5.75). It is an antidiabetic agent. | |||
T9014 | SKI-178 | Apoptosis , S1P Receptor | |
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ... | |||
T9714 | Atpenin A5 | Potassium Channel | |
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1]. | |||
T4316 | ML365 | Potassium Channel | |
ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3). | |||
T0343 | Nimodipine | BAY-e 9736 | Glucocorticoid Receptor , AhR , Calcium Channel , Autophagy |
Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells. | |||
T1781 | GW9508 | GW 9508 | GPR , Potassium Channel |
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner. | |||
T1198 | Tetracaine hydrochloride | Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl | Calcium Channel , Sodium Channel |
Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been use... | |||
T26795 | PXS-4728A | BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl | Monoamine Oxidase |
BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive pulmonary disease in mice[2]. | |||
T1603 | Glipizide | CP 28720,K 4024 | Potassium Channel , PPAR , ABC |
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity. | |||
T1634 | Glibenclamide | Glyburide | Potassium Channel , Mitochondrial Metabolism , CFTR , P-gp , Autophagy |
Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide. | |||
T1952 | MK-2206 dihydrochloride | MK-2206 2HCl | Apoptosis , Akt , Autophagy |
MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor a... | |||
T1101 | Minocycline hydrochloride | Minocycline HCl | HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic |
Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor... | |||
T11979 | McN5691 | RWJ26240 | Calcium Channel |
McN5691 is a voltage sensitive calcium channel blocker. | |||
T23233L | RETF-4NA acetate | RETF-4NA acetate(1160928-63-1 free base) | Others |
RETF-4NA acetate is a sensitive, specific substrate for chymotrypsin. | |||
T14999 | CORM-401 | Others | |
CORM-401 is an oxidant-sensitive CO-releasing molecule. It can be used in oxidative stress-mediated pathologies and the research of inflammatory. | |||
T74235 | DHAPC | ||
DHAPC is a phospholipid that is very sensitive to oxidation [1] . | |||
TQ0150 | Levcromakalim | (-)-Cromakalim,BRL 38227 | Potassium Channel |
Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel. | |||
T10566 | BMS-191095 | Potassium Channel | |
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator. | |||
T20968 | CyPPA | Potassium Channel , Dopamine Receptor | |
CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolarization. | |||
T18974 | DiBAC4(3) | Others | |
DiBAC4(3) is a voltage-sensitive fluorescent dye (λem=505 nm, λex=490 nm). |