Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 mg | In stock | $ 48.00 | |
500 mg | In stock | $ 72.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity. |
Targets&IC50 | KATP:6.4 nM ATP-sensitive potassium (IC50) |
Kinase Assay | The activity of caspase-3, -8 and -9 is assessed using the caspase-3, -8 and -9 colorimetric assay kits, respectively. In brief, 1×106?cells in a 60-mm culture dish are incubated with 10 mM Valproic acid for 24 h. The cells are then washed in PBS and suspended in 5 volumes of lysis buffer provided with the kit. Protein concentrations are determined using the Bradford method. Supernatants containing 50 μg total protein are used to determine caspase-3, -8 and -9 activities. The supernatants are added to each well in 96-well microtiter plates with DEVD-pNA, IETD-pNA or LEHD-pNA as caspase-3, -8 and -9 substrates and the plates are incubated at 37°C for 1 h. The optical density of each well is measured at 405 nm using a microplate reader. The activity of caspase-3, -8 and -9 is expressed in arbitrary absorbance units. |
Synonyms | CP 28720, K 4024 |
Molecular Weight | 445.54 |
Formula | C21H27N5O4S |
CAS No. | 29094-61-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 82 mg/mL (184 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Glipizide 29094-61-9 DNA Damage/DNA Repair Membrane transporter/Ion channel Metabolism Potassium Channel PPAR ABC CP 28720 K 4024 type 2 diabetes sulfonylurea class K ATP KcsA Inhibitor mellitus CP-28720 inhibit K-4024 ATP-sensitive potassium CP28720 pancreatic β K4024 inhibitor