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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9264 | ECBN HCL | 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1) | Others |
ECBN HCL (A-30912A nucleus hydrochloride) is the reaction product catalyzed by Echinocandin B (ECB) deacylase. | |||
T3849 | Kinsenoside | (+)-Kinsenoside | Apoptosis , Nrf2 |
Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities. Kinsenoside could be useful for repairing beta cells in pancreatic islet injury as well as improving its function, it cou... | |||
T7304 | DNQX | FG 9041 | GluR , iGluR |
DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively) | |||
T8459 | DNQX disodium salt | DNQX Disodium | NMDAR , iGluR |
DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptor | |||
T11277 | FG 7142 | ZK 39106,LSU-65 | GABA Receptor |
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cereb... | |||
T4420 | 4-Hydroxytamoxifen | ICI 79280,(Z)-4-hydroxy Tamoxifen,trans-4-Hydroxytamoxifen | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer rese... | |||
T4104 | Ophiopojaponin C | Ophiopogonin C | Others |
Ophiopogonin C' pharmacological activities may be related to the substances in nucleus mainly. | |||
T83651 | AC-263093 | Neuropeptide Y Receptor | |
AC-263093 is an NPFFR2 agonist with anxiolytic activity that increases c-Fos protein expression in the paraventricular nucleus of the hypothalamus. | |||
T12220 | NIC3 | Others | |
NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor,with anti-cancer activity. | |||
T3S1692 | Octahydrocurcumin | Anti-infection , NF-κB , Reactive Oxygen Species , ROS | |
Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy... | |||
T1844 | KPT330,(E)- | (E)-RN,KPT-330,KPT330,KPT 330 | Others , CRM1 |
(E)-RN (KPT 330) is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells. | |||
T23854 | Carbidine | Carbidine dihydrochloride,Karbidin,Carbidin,Karbidine | Others |
Carbidine (Carbidin) is a derivative of gamma-carboline, an atypical antipsychotic drug. It reduces the inhibitory effect of DA on the 3H-DA release from synaptosomes of the nucleus accumbens septi and on the activity of... | |||
TP1653L | SV40 T-Ag-derived NLS peptide acetate | SV40 T-Ag-derived NLS peptide acetate(105425-98-7 free base) | Others |
SV40 T-Ag-derived NLS peptide acetate (SV40 T-Ag-derived NLS peptide acetate) is a nuclear localization signal peptide. The DNA labeled with this peptide can be effectively transferred to the nucleus. | |||
T1127 | Beclometasone dipropionate | Beclovent,Beclomethasone dipropionate,Beconase,Vancenase | Glucocorticoid Receptor |
Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone... | |||
T2162 | Maribavir | BW1263W94,GW257406X,Benzimidavir,1263W94 | Others , HCV Protease |
Maribavir (GW257406X) is an orally available benzimidazole riboside compound with activity against cytomegalovirus (CMV). Maribavir is a selective ATP competitor of the viral UL97 kinase, which is involved in viral nucle... | |||
T10904 | CWP232228 | Wnt/beta-catenin | |
CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting t... | |||
T64317 | ZZL-7 | Serotonin Transporter | |
ZZL-7 is a fast-onset antidepressant agent. ZZL-7 disrupts the interaction between the neuronal nitric oxide synthase (nNOS) and serotonin transporter (SERT) in the dorsal raphe nucleus (DRN). ZZL-7 can easily cross the ... | |||
T16538 | PIN1 inhibitor API-1 | Others | |
PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM). PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from the nucleus to cytoplasm, th... | |||
T5S1805 | 5,7-Dihydroxychromone | 5,7-Dihydroxy-4H-Chromen-4-One | Others , Virus Protease , PARP , Caspase , Nrf2 |
1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai... | |||
T1168 | Desonide | Tridesilon,Locapred,Prednacinolone | Glucocorticoid Receptor |
Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated ... |