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Beclometasone dipropionate

Catalog No. T1127 CAS 5534-09-8

Synonyms: Beclovent, Beclomethasone dipropionate, Beconase, Vancenase

Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production.

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Beclometasone dipropionate Chemical Structure

Beclometasone dipropionate, CAS 5534-09-8

Pack Size	Availability	Price/USD
100 mg	In stock	$ 31.00
200 mg	In stock	$ 46.00
250 mg	In stock	$ 50.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.44%

Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

In vitro

Beclomethasone dipropionate (BDP) is an anti-inflammatory corticosteroid available for the treatment of asthma and allergic rhinitis (AR). BDP is previously developed as aqueous nasal formulations for the treatment of AR. BDP is also available in dry nasal aerosol formulations as chlorofluoro carbon (CFC) metered-dose inhaler nasal sprays, but CFC-containing formulations have been withdrawn from the market and currently are not available.BDP hydrofluoroalkane (HFA) inhalation aerosol currently is available for patient use and indicated for the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older.BDP HFA nasal aerosol, an intranasal aerosol formulation, has been developed recently for the treatment of AR.

Synonyms	Beclovent, Beclomethasone dipropionate, Beconase, Vancenase
Molecular Weight	521.04
Formula	C28H37ClO7
CAS No.	5534-09-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (105.56 mM)

Ethanol: 18 mg/mL (34.55 mM)

References and Literature

1. Ratner PH, et al. Clin Ther, 2012, 34(6), 1422-1431. 2. Busse WW, et al. J Allergy Clin Immunol, 1999, 104(6), 1215-1222.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Clinical Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Drug Repurposing Compound Library Inhibitor Library Orally Active Compound Library Anti-Fibrosis Compound Library Bioactive Compound Library Anti-Metabolism Disease Compound Library FDA-Approved & Pharmacopeia Drug Library

Related Products

Related compounds with same targets

Relacorilant Prednisone acetate Deoxycorticosterone acetate Glucagon (1-29), bovine, human, porcine hydrochloride Flumethasone Fluocinolone (Acetonide) Desonide Triamcinolone

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Keywords

Beclometasone dipropionate 5534-09-8 Endocrinology/Hormones Glucocorticoid Receptor Beclomethasone Dipropionate iNOS 16HBE cells STAT-1 Beclovent Beclomethasone dipropionate Beclometasone Dipropionate Beconase Beclomethasone Inhibitor Beclometasone inhibit Vancenase asthma inflammation inhibitor

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