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20

Compounds

Cat No. Product Name Synonyms Targets
T64006 Lipid-lowering agent-1
Lipid-lowering agent-1 is a potent lipid-lowering agent that significantly inhibits the pharmacological effects of low-density lipoprotein cholesterol (LDLC) and promotes the production of high-density lipoprotein choles...
T2824 Pedunculoside Others , Fatty Acid Synthase
Pedunculoside is extracted from Ilex rotunda Thunb.
T4039 BIBB 515 Others
BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of...
T10900 CUDA PPAR , Epoxide Hydrolase
CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR...
T0022 Taurine 2-Aminoethanesulfonic acid LDL , Endogenous Metabolite , Autophagy
Taurine (2-Aminoethanesulfonic acid), an organic acid, is distributed in various animal tissues.
T3978 Linerixibat GSK2330672,Iinerixibat HBV
Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.
T0683 Mevastatin Compactin,ML236B Apoptosis , Antibacterial , Antibiotic , HMG-CoA Reductase , Autophagy , Lipid
Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
T0106 Methazolamide L584601,CL 8490 Carbonic Anhydrase
Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
T7133 Anagliptin SK-0403 Proteasome , DPP-4
Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.
T7486 Imeglimin hydrochloride EMD 387008 hydrochloride Reactive Oxygen Species , Mitochondrial Metabolism
Imeglimin hydrochloride (EMD 387008 hydrochloride) prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.
T1035 Hesperidin Hesperetin 7-rutinoside,Cirantin Apoptosis , Reactive Oxygen Species , Endogenous Metabolite , Autophagy
Hesperidin (Cirantin) is a flavanone glycoside found in citrus fruits with antioxidant, anti-inflammatory, anti-carcinogenic, and antihypertensive and lipid-lowering activity.
T61151 Beclobrate
Beclobrate (Sgd 24774), a fibric acid derivative, exhibits potent lipid-lowering efficacy in rodent models [1].
T0241 Sulfacarbamide Sulfanilylurea Others
Sulfacarbamide (Sulfanilylurea) is a blood sugar-lowering agent.
T9010 IMM-H007 Others , AMPK
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
T1207 Lovastatin MK-803,Mevinolin Ferroptosis , HMG-CoA Reductase , Autophagy
Lovastatin (MK-803) is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.
TP1062L Katacalcin acetate(85916-47-8 free base) PDN 21 acetate Others
Katacalcin acetate(85916-47-8 free base) (PDN 21 acetate) is a potent plasma calcium-lowering peptide.
T15549 Icosabutate Others
Icosabutate is a structurally engineered and orally active ω-3 polyunsaturated fatty acid. Icosabutate is well tolerated, and efficacious in lowering non-high-density lipoprotein cholesterol (non-HDL-C) levels in persist...
T13563 AZ-1355 Prostaglandin Receptor
AZ-1355 is a novel dibenzoxepine derivative with lipid-lowering properties.
T4509 Inositol nicotinate Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,Dilexpal,Inositol hexanicotinate Others
Inositol nicotinate (Mesotal) has the effect of lowering cholesterol and expanding peripheral blood vessels for hypercholesterolemia and atherosclerosis.
T14690 BMS 433796 BMS-289948,BMS-299897 Beta Amyloid
BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.

Compounds

Lipid-lowering agent-1
T64006
Synonym:
Target:
Pedunculoside
T2824
Synonym:
Target: Others, Fatty Acid Synthase
BIBB 515
T4039
Synonym:
Target: Others
CUDA
T10900
Synonym:
Target: PPAR, Epoxide Hydrolase
Taurine
T0022
Synonym: 2-Aminoethanesulfonic acid
Target: LDL, Endogenous Metabolite, Autophagy
Linerixibat
T3978
Synonym: GSK2330672,Iinerixibat
Target: HBV
Mevastatin
T0683
Synonym: Compactin,ML236B
Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid
Methazolamide
T0106
Synonym: L584601,CL 8490
Target: Carbonic Anhydrase
Anagliptin
T7133
Synonym: SK-0403
Target: Proteasome, DPP-4
Imeglimin hydrochloride
T7486
Synonym: EMD 387008 hydrochloride
Target: Reactive Oxygen Species, Mitochondrial Metabolism
Hesperidin
T1035
Synonym: Hesperetin 7-rutinoside,Cirantin
Target: Apoptosis, Reactive Oxygen Species, Endogenous Metabolite, Autophagy
Beclobrate
T61151
Synonym:
Target:
Sulfacarbamide
T0241
Synonym: Sulfanilylurea
Target: Others
IMM-H007
T9010
Synonym:
Target: Others, AMPK
Lovastatin
T1207
Synonym: MK-803,Mevinolin
Target: Ferroptosis, HMG-CoA Reductase, Autophagy
Katacalcin acetate(85916-47-8 free base)
TP1062L
Synonym: PDN 21 acetate
Target: Others
Icosabutate
T15549
Synonym:
Target: Others
AZ-1355
T13563
Synonym:
Target: Prostaglandin Receptor
Inositol nicotinate
T4509
Synonym: Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,Dilexpal,Inositol hexanicotinate
Target: Others
BMS 433796
T14690
Synonym: BMS-289948,BMS-299897
Target: Beta Amyloid
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TargetMol