Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Imeglimin hydrochloride (EMD 387008 hydrochloride) prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 79.00 | |
10 mg | In stock | $ 126.00 | |
25 mg | In stock | $ 229.00 | |
50 mg | In stock | $ 383.00 | |
100 mg | In stock | $ 578.00 | |
500 mg | In stock | $ 1,220.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 217.00 |
Description | Imeglimin hydrochloride (EMD 387008 hydrochloride) prevents human endothelial cell death by inhibiting mitochondrial permeability transition without inhibiting mitochondrial respiration. |
In vitro | Imeglimin dramatically decreased reactive oxygen species production, inhibiting specifically reverse electron transfer through complex I. Imeglimin prevents hyperglycemia-induced cell death in HMEC-1 through inhibition of PTP opening without inhibiting mitochondrial respiration nor affecting cellular energy status[1]. |
Synonyms | EMD 387008 hydrochloride |
Molecular Weight | 191.66 |
Formula | C6H14ClN5 |
CAS No. | 775351-61-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25 mg/mL (130.44 mM)
You can also refer to dose conversion for different animals. More
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Imeglimin hydrochloride 775351-61-6 Immunology/Inflammation Metabolism NF-Κb Reactive Oxygen Species Mitochondrial Metabolism EMD387008 EMD 387008 hydrochloride inhibit mitochondrial lowering insulin oral Imeglimin Hydrochloride ROS Imeglimin Inhibitor function EMD-387008 EMD387008 Hydrochloride sensitivity EMD 387008 EMD 387008 Hydrochloride EMD-387008 Hydrochloride glucose inhibitor