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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T83625 | iNOS-IN-14 | 3-bromo-1H-indazole-7-carbonitrile | NOS |
iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) is a potent nitric oxide synthase (NOS) inhibitor that inhibits the NADPH oxidase activity of nNOS. | |||
T72638 | iNOS inhibitor-10 | NO Synthase | |
iNOS Inhibitor-10, with an IC50 of 65 nM, exhibits antiproliferative effects on triple-negative breast cancer cells [1]. | |||
T62849 | iNOS-IN-2 | ||
iNOS-IN-2 (Compound 53) is a potent inducible nitric oxide synthase (iNOS) protein down-regulator. iNOS-IN-2 effectively inhibits NO production (IC50: 6.4 μM). iNOS-IN-2 can be used in studies of chronic inflammation. | |||
T62987 | iNOs-IN-1 | ||
iNOs-IN-1 (YPW) is a potent inhibitor of inducible nitric oxide synthase (iNOS) with anti-inflammatory effects. iNOs-IN-1 significantly inhibits IL-6 and iNOS expression in a dose-dependent manner in murine macrophages, ... | |||
T63261 | iNOs-IN-3 | ||
iNOs-IN-3 is an orally active nitric oxide synthase (iNOS) inhibitor with an IC50 value of 3.342 μM that exhibits anti-inflammatory effects and can be used to study LPS-induced acute lung injury (ALI). | |||
T63104 | iNOS/PGE2-IN-1 | ||
iNOS/PGE2-IN-1 is an iNOS/PGE2 inhibitor and a potent anti-inflammatory agent. iNOS/PGE2-IN-1 exhibits an inhibitory effect on LPS-induced NO production and has a low ulcerogenic potential. | |||
T6S1665 | Irisflorentin | Others , NO Synthase | |
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan... | |||
T2738 | Dehydroandrographolide | NOS , Influenza Virus | |
Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees. | |||
TN6951 | Ethyl linoleate | Others | |
Ethyl linoleate is a natural product. | |||
T6S1572 | Sauchinone | ERK , p38 MAPK , NF-κB | |
1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative... | |||
TN2139 | Regaloside B | NOS , COX , NO Synthase | |
Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2). | |||
T0610 | Piceatannol | trans-Piceatannol,Astringenin | Apoptosis , Serine/threonin kinase , PKA , Syk , PKC , Autophagy |
Piceatannol (Astringenin) is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases and inhibits NF-κB activation and gene expression of TNF-induced. It is... | |||
T21700 | NOS-IN-1 | 2-Imino-4-methylpiperidine (acetate) | NOS |
NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectiv... | |||
T19916 | TRIM | 1-(2-Trifluoromethylphenyl)imidazole | NOS |
TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS. | |||
T5S0045 | Isofraxidin | 6,8-Dimethoxyumbelliferone,Phytodolor | MMP , ERK , p38 MAPK , TLR , COX |
1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote... | |||
T1079 | Metronidazole | Flagyl,Metronidazol,Anagiardil | Apoptosis , NADPH , Hydrogenase , Antibacterial , Antibiotic , Parasite , Antifection |
Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. | |||
T1127 | Beclometasone dipropionate | Beclovent,Beclomethasone dipropionate,Beconase,Vancenase | Glucocorticoid Receptor |
Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone... | |||
T22419 | S-Methylisothiourea sulfate | (S)-Methylisothiourea sulfate | NOS , NO Synthase , HSV |
S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) is a potent and selective inhibitor of iNOS and exerts beneficial effects in rodent models of septic shock[1]. | |||
T23046 | N-tert-butyl-α-Phenylnitrone | (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide | ROS , COX |
N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) possesses potent reactive oxyge... | |||
TCS2170 | 2,5-Dihydroxyacetophenone | Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP | ERK , NF-κB , Tyrosinase |
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK... |