duration — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16136	MRS-1706		Adenosine Receptor
	MRS-1706 has Ki values of 1.39, 112, 157, and 230 nM for human A2B, A2A, A1, and A3 receptors respectively. MRS-1706 is an effective and selective adenosine A2B receptor inverse agonist.		Adenosine Receptor
T8581	Flecainide hydrochloride		Others
	Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.		Others
T3S0081	Oxypeucedanin	(+-)-Oxypeucedanin,Oxypeucadanin	Potassium Channel
	1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocke...		Potassium Channel
T0802	Procaine hydrochloride	Novocaine HCl,Procaine HCl	Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR
	Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel...
T22371	Mivacurium dichloride	Mivacurium chloride	AChR
	Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emerg...		AChR
T0029	Procaine	Duracaine,Spinocaine,Novocaine,Vitamin H3	Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
	Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.		Histone Demethylase , DNA/RNA Synthesis , Sodium Channel
T0015	Mephenesin	Cresoxydiol,Memphenesin,Mephedan,Decontractyl	NMDAR , iGluR
	Mephenesin (Cresoxydiol) is a centrally acting muscle relaxant with a short duration of action.		NMDAR , iGluR
T20968	CyPPA		Potassium Channel , Dopamine Receptor
	CyPPA, a subtype-selective positive modulator of SK channels, decreased spontaneous firing rate, increased the duration of the apamin-sensitive afterhyperpolarization.		Potassium Channel , Dopamine Receptor
T0916	Butamben	Butyl 4-aminobenzoate	Potassium Channel , Calcium Channel , Sodium Channel
	Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.		Potassium Channel , Calcium Channel , Sodium Channel
T28829	Soquinolol	Soquinolol mucate	Adrenergic Receptor
	Soquinolol (Soquinolol mucate) is a beta-adrenergic receptor antagonist with weak local anesthetic activity.Soquinolol has good enteral efficacy and a long duration of action.		Adrenergic Receptor
T0780	Pyridostigmine bromide	Mestinon	AChE
	Pyridostigmine bromide (Mestinon) is a cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.		AChE
T7198	E-4031		EGFR , Potassium Channel
	E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)		EGFR , Potassium Channel
T5585	AM-92016 hydrochloride		Potassium Channel
	AM-92016 is a specific blocker of rectifier potassium current. AM-92016 delays rectifier potassium channel and repolarizes the membrane thereby restricting the duration of the nerve impulse.		Potassium Channel
T4250	Bilastine	Bilaxten	Histamine Receptor
	Bilastine (Bilaxten) is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.		Histamine Receptor
T6397	Atracurium besylate	Tracrium,51W89,BW-33A	AChR
	Atracurium besylate (51W89) is a non-depolarizing neuromuscular blocking agent with short duration of action. Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for eliminat...		AChR
T4497	Amifampridine	3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine	Others
	Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ...		Others
T19735	Flucycloxuron	(E)-flucycloxuron,Andalin	Others
	Flucycloxuron ((E)-flucycloxuron) is a chitin synthesis inhibitor used as a pesticide. In insect models, the inhibitor has been shown to affect several reproductive events such as the duration of preovipostion.		Others
T1439	Lacidipine	SN-305,GX-1048,GR-43659X	Apoptosis , Calcium Channel , Reactive Oxygen Species
	Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi...		Apoptosis , Calcium Channel , Reactive Oxygen Species
T21335	Fluorogestone acetate	Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880	Others
	Fluorogestone acetate (Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880) showed a high potency with short duration of activity and performed physiologically similar to progesterone. FGA was approxim...		Others
T3574	Sematilide hydrochloride	CK-1752A,CK-1752,Sematilide HCl	Potassium Channel
	Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the ...		Potassium Channel