Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Soquinolol (Soquinolol mucate) is a beta-adrenergic receptor antagonist with weak local anesthetic activity.Soquinolol has good enteral efficacy and a long duration of action.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 146.00 | |
5 mg | In stock | $ 350.00 | |
10 mg | In stock | $ 530.00 | |
25 mg | In stock | $ 859.00 | |
50 mg | In stock | $ 1,180.00 | |
100 mg | In stock | $ 1,590.00 | |
500 mg | In stock | $ 3,190.00 |
Description | Soquinolol (Soquinolol mucate) is a beta-adrenergic receptor antagonist with weak local anesthetic activity.Soquinolol has good enteral efficacy and a long duration of action. |
In vitro | Soquinolol inhibits the isoprenaline-induced tachycardia (EC50% = 48 μg/L) in the guinea-pig Langendorff heart in vitro.[2] |
In vivo | Soquinolol (5.5 μg/kg; intravenous injection; conscious dog) beta 1-adrenergic blocking activity (ED 50%) and oral administration (5.8 μg/kg; oral) is about twice as great as that of pindolol and 19 times (i.v.). These results suggest 95% enteral efficacy for soquinolol (pindolol 88%, propranolol 13%). The differences in soquinolol's and propranolol's efficacy detected in vitro and in vivo are partially attributable to differences in their kinetic properties namely the lower protein binding and the higher distribution volume of soquinolol. In the conscious dog, soquinolol inhibits beta 1-(ED 50% = 4.0 μg/kg) and beta 2 receptors (ED 50% = 2.7 μg/kg) at dose levels which do not differ significantly.[2] |
Synonyms | Soquinolol mucate |
Molecular Weight | 306.4 |
Formula | C17H26N2O3 |
CAS No. | 61563-18-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (146.87 mM)
You can also refer to dose conversion for different animals. More
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Soquinolol 61563-18-6 GPCR/G Protein Neuroscience Adrenergic Receptor Soquinolol mucate inhibitor inhibit