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Bilastine

Catalog No. T4250 CAS 202189-78-4

Synonyms: Bilaxten

Bilastine (Bilaxten) is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.

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Bilastine, CAS 202189-78-4

Pack Size	Availability	Price/USD
25 mg	In stock	$ 39.00
50 mg	In stock	$ 64.00
100 mg	In stock	$ 105.00
200 mg	In stock	$ 155.00
500 mg	In stock	$ 262.00

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Purity: 99.61%

Purity: 99.59%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Bilastine (Bilaxten) is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Targets&IC50	H1 receptor(guinea-pig cerebellum):44.15 nM(Ki)
In vitro	Bilastine has a highly selective affinity for the H1-receptor but a very low affinity for 30 other tested receptors. It isn't obvious inhibitory against bradykinin, serotonin, muscarinic M3-receptors, leukotriene D4, calcium, α1-adrenoceptors, β2-adrenoceptors, and H2- and H3- receptors.
In vivo	In patients with allergic rhinoconjunctivitis, Bilastine is efficacious in all nasal symptoms including obstruction and in eye symptoms. In the fasting state, Bilastine is quickly absorbed, but the absorption is slowed when it is taken with food or fruit juice.

Synonyms	Bilaxten
Molecular Weight	463.61
Formula	C28H37N3O3
CAS No.	202189-78-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Slightly soluble

References and Literature

1. Wolthers OD.Bilastine: a new nonsedating oral H1 antihistamine for treatment of allergic rhinoconjunctivitis and urticaria.Biomed Res Int. 2013;2013:626837.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Drug Repurposing Compound Library EMA Approved Drug Library Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Anti-Cancer Compound Library Nonsteroidal Anti-Inflammatory Compound Library Pediatric Drug Library ReFRAME Related Library

Related Products

Related compounds with same targets

Antazoline hydrochloride Metoprine Rocastine Betahistine mesylate GSK-239512 Protopine HTMT dimaleate KSK94 FA

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Bilastine 202189-78-4 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor Inhibitor inhibit Bilaxten inhibitor

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