Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of refractoriness and action potential duration.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 32.00 | |
2 mg | In stock | $ 45.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 113.00 | |
25 mg | In stock | $ 228.00 | |
50 mg | In stock | $ 372.00 | |
100 mg | In stock | $ 597.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 84.00 |
Description | Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of refractoriness and action potential duration. |
Targets&IC50 | K+ current:25 μM (IC50) |
Synonyms | CK-1752A, CK-1752, Sematilide HCl |
Molecular Weight | 349.87 |
Formula | C14H24ClN3O3S |
CAS No. | 101526-62-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (157.2 mM)
You can also refer to dose conversion for different animals. More
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Sematilide hydrochloride 101526-62-9 Membrane transporter/Ion channel Potassium Channel CK1752 CK 1752 antiarrhythmic channel blocker Sematilide Inhibitor KcsA inhibit current CK-1752A Sematilide Hydrochloride CK-1752 Sematilide HCl IKr inhibitor