cytoplasmic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14965	Ciliobrevin D		ATPase , Hedgehog/Smoothened
	Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity ...		ATPase , Hedgehog/Smoothened
TP1563	Gap19		Gap Junction Protein
	Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.		Gap Junction Protein
T4074	GSK-872	GSK872,GSK'872,GSK2399872A	RIP kinase
	GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).		RIP kinase
T77349	CCR1/5/8 activator 1		Phospholipase
	CCR1/5/8 activator 1 is a cytoplasmic phospholipase A inhibitor with antifungal activity.		Phospholipase
T10065L	2',3'-cGAMP sodium	2'-3'-cyclic GMP-AMP sodium	STING , cGAS
	2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium), a cGAMP synthase (cGAS) affecting cytoplasmic DNA production as a second messenger, is a transmembrane bridging protein that is a key component of the cellular innate imm...		STING , cGAS
T13881	Dicirenone	SC26304	ATPase , Glucocorticoid Receptor
	Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasmic and nuclear receptors.		ATPase , Glucocorticoid Receptor
T19343	Sn-Glycerol 3-phosphate	Glycerol 3-phosphate,sn-Glycerol 3-phosphate lithium salt	Endogenous Metabolite
	sn-Glycerol 3-phosphate is produced by the reduction of dihydroxyacetone phosphate by NADH formed during glycolysis of the cytoplasmic glycerol 3-phosphate dehydrogenase pathway.		Endogenous Metabolite
T20913	Light Green SF Yellowish	Acid Green 5,C.I. Acid Green 5,C.I. 42095
	Light Green SF Yellowish (Acid Green 5) is an alkaline stain used for staining animal tissues and for cytoplasmic and fiber staining in plant histology.
T2274	SC79	SC 79	Akt
	SC79 is an AKT agonist with specificity and blood-brain barrier permeability. SC79 specifically binds to the PH domain of AKT, activates cytoplasmic AKT, and inhibits AKT membrane translocation. SC79 has neuroprotective ...		Akt
T1429	17α-Hydroxyprogesterone	Hydroxyprogesterone,17-OHP,17-Hydroxyprogesterone	Estrogen/progestogen Receptor , Progesterone Receptor , Endogenous Metabolite
	17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to th...
T25214	CCR-11	CCR11,CCR 11	Antibiotic
	CCR-11 is a tannin-containing derivative with antimicrobial activity. CCR-11 inhibits the proliferation of B. subtilis and HeLa cells. CCR-11 inhibits bacterial proliferation and bacterial cytoplasmic division by inhibit...		Antibiotic
T0187	Amorolfine hydrochloride	Amorolfin,Amorolfine HCl,Ro 14-4767/002	Antibiotic , Antifungal
	Amorolfine hydrochloride (Amorolfine HCl) is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function an...		Antibiotic , Antifungal
TQ0302	Thapsigargin		Apoptosis , SARS-CoV , Calcium Channel
	Thapsigargin is a natural product, an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) and an endoplasmic reticulum stress inducer. Thapsigargin increases cytoplasmic calcium concentration by blocking ...		Apoptosis , SARS-CoV , Calcium Channel
T38722	(Z)-PUGNAc		Others
	(Z)-PUGNAc is a potent O-GlcNAcase inhibitor that is more active than (E)-PUGNAc, removes O-GlcNAc from proteins (peptide O-GlcNAc-β-N-acetylaminoglucosidase), and can be used to increase the levels of O-GlcNAc on nuclea...		Others
T61428	4-PQBH		Others
	4-PQBH is a potent Nur77-binding agent with antitumour activity.4-PQBH inhibits xenograft tumours through Nur77-mediated endoplasmic stress and autophagy by broadly inducing cysteoaspartase-independent cytoplasmic vacuol...		Others
T15183	Dynarrestin		Hedgehog/Smoothened
	Dynarrestin is an inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells. It inhibits dynein 1-driven microtubule gliding in vitro pl...		Hedgehog/Smoothened
T1561	Clobetasol propionate	Dermovate,Clobetasol 17-propionate,CGP9555,Temovate,CCl 4725	Glucocorticoid Receptor , P450
	Clobetasol propionate (CGP9555) exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor-mediated gene expression. This results in the synthesis of certain a...		Glucocorticoid Receptor , P450
TP1565L1	Foxy-5 Ammonium Salt	Foxy-5 Ammonium Salt（881188-51-8 Free base)	Wnt/beta-catenin
	Foxy-5 Ammonium Salt is a WNT5A agonist, a mimetic peptide of WNT5A, a non-classical member of the Wnt family.Foxy-5 Ammonium Salt triggers cytoplasmic free calcium signaling without affecting β-catenin activation and in...		Wnt/beta-catenin
T6529	Halobetasol propionate	Halobetasol Propionate,Ulobetasol propionate,BMY-30056,CGP-14458	Phospholipase
	Halobetasol propionate (BMY-30056) is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses acr...		Phospholipase
T1666	Fludrocortisone acetate	9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,9α-fluorocortisol acetate	Glucocorticoid Receptor , Autophagy
	Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-respon...		Glucocorticoid Receptor , Autophagy