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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9073 | SRS16-86 | Ferroptosis | |
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis. | |||
T4612 | NS309 | EGFR , Potassium Channel , HER | |
NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat... | |||
T8918 | Feruloylputrescine | Others | |
Feruloylputrescine is a natural product. | |||
T5S0246 | Pseudoprotodioscin | Others , Fatty Acid Synthase | |
1. Pseudoprotodioscin has moderate cytotoxicity. | |||
T68139 | Scio-323 | p38 MAPK | |
Scio-323 is an orally available p38 mitogen-activated protein (MAPK) kinase inhibitor. | |||
T0185 | Escitalopram | Seroplex,S-(+)-Citalopram,(S)-Citalopram | Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor |
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien... | |||
T6368 | Abscisic Acid | Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin) | Others , Proton pump , Endogenous Metabolite |
Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth. | |||
T8846 | Beta-Escin | B-escin,AESCINE | Immunology/Inflammation related |
beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent. | |||
T9422 | Fosciclopirox | CPX-POM | Gamma-secretase |
Fosciclopirox (CPX-POM), the phosphoryloxymethyl ester of CPX (Ciclopirox Prodrug, CPX-POM), selectively delivers the active metabolite, CPX, to the entire urinary tract following parenteral administration. | |||
T5177 | Asciminib | ABL001 | Bcr-Abl |
Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5–0.8nM). | |||
T0278 | Escin | Aescin | Apoptosis , Others |
Escin (Aescin) is biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of Aesculus. | |||
T3932 | Viscidulin I | Others | |
Viscidulin I is found in Scutellaria baicalensis and is a natural product. | |||
TN1777 | Isoescin IB | Others | |
Isoescin IB is a natural product from Aesculus hippocastanum L. | |||
T7508 | N-Acetylputrescine hydrochloride | Endogenous Metabolite | |
N-Acetylputrescine is a polyamine commonly occurring excreted in normal human urine | |||
T2321 | Protodioscin | Furostanol I | Androgen Receptor , Endogenous Metabolite |
Protodioscin (Furostanol I) is a major steroidal saponin in dioscoreae rhizome, with anti-hyperlipidemia, anti-cancer properties. | |||
T20657 | Muscimol HBr | Agarin hydrobromide,Muscimol Hydrobromide,Agarin HBr | GABA Receptor |
Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor. | |||
T4429 | Rauwolscine hydrochloride | Corynanthidine hydrochloride,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride | Adrenergic Receptor |
Rauwolscine hydrochloride (Isoyohimbine hydrochloride) , a natural alkaloid, is a specific and reversible α2-adrenergic receptor antagonist (Ki: 12 nM) [1]. It is a stereoisomer of yohimbine, which potently antagonizes b... | |||
T3027 | Sodium Aescinate | Escin sodium salt | HIF |
Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii. | |||
T3019 | Physcion | Physcione,Parietin,Rheochrysidin | Dehydrogenase , Antibacterial |
Physcion (Physcione) (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM... | |||
TN2107 | Protoescigenin | Others | |
Protoescigenin is from horse chestnut saponin mixture and can be used as the substrate for exploratory chemistry towards selective protection. |