rax — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP2350	RA X Peptide	RAX,RA-X,RA X
	RA X Peptide is used as an antitumor cyclic hexapeptide.
T3783	Fraxin	Fraxoside,Fraxetin-8-O-glucoside,Paviin	OAT , transporter , PDE
	Fraxin (Fraxoside) is a glucoside of fraxetin.		OAT , transporter , PDE
T6840	FRAX486		PAK
	FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.		PAK
T3770	Taraxasterol	Taraxasterin	IL Receptor , TNF , NO Synthase , Prostaglandin Receptor
	Taraxasterol (Taraxasterin) is compound with anti-inflammatory activity.		IL Receptor , TNF , NO Synthase , Prostaglandin Receptor
T6014	FRAX597		PAK
	FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).		PAK
T34268	Raxofelast	IRFI016,IRFI-016,IRFI 016
	Raxofelast (IRFI-016) is a hydrophilic, non-systemic, vitamin-like antioxidant that reduces ischemia-reperfusion injury in testis. Raxofelast is a good candidate compound for stopping oxidative stress after acute testicu...
T5781	Taraxasteryl acetate		Antibacterial
	Taraxasterol acetate has anti-inflammatory activity in bino rats against carrageenan, formaldehyde and adjuvant induced inflammations. Taraxasterol acetate also displays potential antibacterial activities.		Antibacterial
TN2241	Styraxlignolide F		Others
	Styraxlignolide F is a natural product from Styrax japonica.		Others
T6840L	FRAX486 HCL(1232030-35-1 free base)		PAK
	FRAX486 HCL is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.		PAK
T6S0071	Fraxinellone		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
	1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding...		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
T4S2354	Dimethylfraxetin	Fraxetin dimethyl ether,6,7,8-Trimethoxycoumarin	Carbonic Anhydrase
	Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki：0.0097 μM)		Carbonic Anhydrase
T68166L	Traxanox TFA	Traxanox TFA(58712-69-9 Free base)	Others
	Traxanox TFA is an orally available diuretic. Traxanox TFA enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox TFA restores inhibition...		Others
T35028	Valiglurax	VU2957,VU 0652957,VU 2957,VU-0652957,VU0652957,VU-2957	GluR
	Valiglurax (VU2957), also known as VU0652957 and VU2957, is a potent, selective, CNS penetrant, and orally bioavailable mGlu4 PAM. VU2957 possessed attractive in vitro and in vivo pharmacological and DMPK properties acro...		GluR
T5S0045	Isofraxidin	6,8-Dimethoxyumbelliferone,Phytodolor	MMP , ERK , p38 MAPK , TLR , COX
	1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote...		MMP , ERK , p38 MAPK , TLR , COX
T6839	FRAX1036		PAK
	FRAX-1036 is a effective and selective PAK1 inhibitor.		PAK
T2909	Fraxetin	7,8-dihydroxy-6-methoxy coumarin	Apoptosis , Others
	Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a m...		Apoptosis , Others
T12573	Vipivotide tetraxetan	PSMA-617	Others
	Vipivotide tetraxetan (PSMA-617) is a high potent inhibitor of prostate-specific membrane antigen (PSMA)(Ki of 0.37 nM).		Others
T68166	Traxanox		Others
	Traxanox is an orally available diuretic.Traxanox enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro.Restorative effect of Traxanox on inhibiti...		Others
T33676	Niraxostat	Y 700,Y700,Y-700	Xanthine Oxidase
	Niraxostat (Y-700) is one of the isocytosine derivatives as xanthine oxidase inhibitors.		Xanthine Oxidase
T2342	Raxatrigine	CNV1014802,CNV 1014802,GSK-1014802,CNV-1014802	Sodium Channel
	Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.		Sodium Channel