Home Tools
Log in
Cart

Search Result

Search Results for " c7 "

Targets

78

Compounds

13

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T40004 Pomalidomide-C7-NH2 hydrochloride Others
Pomalidomide-C7-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
T39701 Pomalidomide-C7-COOH Pomalidomide-C7-COOH
Pomalidomide-C7-COOH is a chemically synthesized E3 ligase cereblon ligand-linker conjugate, utilized as an intermediate compound for the synthesis of PROTAC BCL-XL degraders.
T39511 Thalidomide-O-C7-NH2 Thalidomide-O-C7-NH2
Thalidomide-O-C7-NH2 is a synthesized conjugate compound comprising an E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Thalidomide and a linker that is commonly employed in PROTAC...
T39645 Thalidomide-O-C7-acid Thalidomide-O-C7-acid
Thalidomide-O-C7-acid is a compound created through the synthesis of an E3 ligase ligand-linker conjugate. It consists of a cereblon ligand derived from Thalidomide, combined with a linker that is commonly employed in PR...
T39838 (S,R,S)-AHPC-C7-amine VH032-C7-amine,(S,R,S)-AHPC-C7-amine
(S,R,S)-AHPC-C7-amine, also known as VH032-C7-amine, is a chemically synthesized conjugate that functions as an E3 ligase ligand-linker. This compound combines the VH032-based VHL ligand with a specific linker designed f...
T82988 AP-C7
AP-C7 is a selective inhibitor of cGMP-dependent protein kinase II (cGKII) with a pIC50 value of 5.0, demonstrating only weak inhibition of cGKII-dependent anion secretion [1].
T18671 (S,R,S)-AHPC-Me-C7 ester Others
(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1].
T77917 Thalidomide-4-O-C7-NH2 hydrochloride
Thalidomide-4-O-C7-NH2 hydrochloride, a Thalidomide-based cereblon ligand, plays a role in the recruitment of CRBN protein and, when linked to a protein ligand, forms PROTACs [1].
T77954 Thalidomide-5-O-C7-NH2 hydrochloride
Thalidomide-5-O-C7-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates CRBN protein recruitment. This compound can be tethered to a protein-targeting ligand using a linker, enabling the formation of PROTA...
T83954 VH 032 amide-alkylC7-acid (S,R,S)-AHPC-amido-C7-acid
VH 032 amide-alkylC7-acid is a specialized compound designed for PROTAC research and development, serving as a functionalized von-Hippel-Lindau (VHL) protein ligand. It combines an E3 ligase ligand with an alkylC7 linker...
T19663 Triheptanoin UX 007,IND106011,UX007,UX-007,IND 106011,IND-106011 Others
Triheptanoin (IND 106011) is a fatty acid metabolic modulator. It potentially for the treatment of fatty acid oxidation disorders and GLUT1.
T10727 Cdc7-IN-5 CDK
Cdc7-IN-5 is a potent inhibitor of Cdc7 kinase. Cdc7, a serine-threonine protein kinase enzyme, is essential for the initiation of DNA replication in the cell cycle.
T11828 LDC7559 Pyroptosis
LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.
T11372 GC7 Sulfate Autophagy
GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS act...
T50125 Compound C749
Compound C749 is a useful organic compound for research related to life sciences. The catalog number is T50125 and the CAS number is 57-03-4.
T23867 Cdc7-IN-7c Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c CDK
Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer.
T15648 KDM5-C70 Histone Demethylase
KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide e...
T16355 NSC781406 PI3K , mTOR
NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).
T2274 SC79 SC 79 Akt
SC79 is an AKT agonist with specificity and blood-brain barrier permeability. SC79 specifically binds to the PH domain of AKT, activates cytoplasmic AKT, and inhibits AKT membrane translocation. SC79 has neuroprotective ...
T24557 NSC756093 NSC-756093,NSC 756093 Others
NSC756093 potentially inhibits GBP1:PIM1 interaction. NSC756093 can be used in ovarian cancer studies.
T10656 Trans-C75 (±)-C75 Others , Fatty Acid Synthase
trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).
T10657 C75 C-75 Fatty Acid Synthase
C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).
T3463 NVP-ACC789 ACC-789,ZK202650 VEGFR , PDGFR
ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases.
TP1166 ZINC77292789 Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH Others
ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC7729...
T60164 UNC7467 Others
UNC7467 is a potent IP6K inhibitor with values of 4.9, 8.9 and 1320 nM for IP6K2, IP6K1 and IP6K6, respectively. UNC7467 reduces levels of inositol pyrophosphates without significantly perturbing levels of other inositol...
T6661 SC75741 Influenza Virus , NF-κB
SC75741 is a potent P65 inhibitor with IC50 of 200 nM
T10729 Cdc7-IN-7 CDK
Cdc7-IN-7 is a potent inhibitor of Cdc7 kinase.
TQ0235 AC710 FLT , PDGFR , c-Kit
AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).
T3084 SGC707 Histone Methyltransferase
SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.
T3169 KC7F2 HIF/HIF Prolyl-Hydroxylase , HIF
KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.
T62921 EBNA1-IN-SC7
EBNA1-IN-SC7 (compound SC7) is a selective inhibitor of Epstein-Barr nuclear antigen 1 (EBNA1) that interferes with EBNA1-DNA binding activity (IC50: 23 μM). Barr virus (EBV) related cancers.
T61289 Cdc7-IN-14
Cdc7-IN-14 (compound 82) is a highly potent inhibitor of CDC7, demonstrating an IC50 value of less than 1 nM. This compound, Cdc7-IN-14, exhibits promising potential for cancer research [1].
T36282 VH 032 amide-alkylC7-amine VH 032 amide-alkylC7-amine
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of funct...
T61435 (S)-Cdc7-IN-18
(S)-Cdc7-IN-18, a potent CDC7 inhibitor, effectively impedes the overactivation of MCM2, a crucial tumor cell marker, induced by huCdc7 overexpression. Consequently, it inhibits the aberrant proliferation of tumor cells....
T74514 HD-TAC7
HD-TAC7, a potent PROTAC HDAC degrader, exhibits IC50 values of 3.6 μM, 4.2 μM, and 1.1 μM for HDAC1, HDAC2, and HDAC3, respectively. It effectively decreases NF-κB p65 in RAW 264.7 macrophages and is utilized in researc...
T61288 Cdc7-IN-13
Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].
T77934 PhosTAC7 PROTACs
PhosTAC7, akin to PROTACs in promoting ternary complex formation, recruits a Ser/Thr phosphatase to a phosphosubstrate to facilitate dephosphorylation.
T79616 UNC7096 Histone Methyltransferase
UNC7096 is a potent, selective degrader of NSD2-PWWP1, exhibiting a dissociation constant (Kd) of 46 nM, and shows promise for treating NSD2-related diseases [1].
T61223 Cdc7-IN-19
Cdc7-IN-19 (compound 1-1) is a potent CDC7 inhibitor with an IC 50 of 1.49 nM [1].
T10724 Cdc7-IN-1 CDK
Cdc7-IN-1 is a highly selective and ATP competitive inhibitor of Cdc7 kinase (IC50: 0.6 nM at 1 mM ATP). It potently inhibits Cdc7 activity in cancer cells and effectively induces cell death.
T71597 JCC76
JCC76 is a selective inhibitor of heat shock protein 27 (Hsp27). JCC76 inhibits the proliferation of human epidermal growth factor 2 (Her2).
T61436 Cdc7-IN-18
Cdc7-IN-18 (compound 1-2) is a highly effective inhibitor of the CDC7 enzyme. It has an IC 50 value of 1.29 nM for the Cdc7/DBF4 enzyme. In addition, this compound exhibits strong antiproliferative activities, with an IC...
T60589 Cdc7-IN-17
Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].
T16354 NSC745885 Others
NSC745885 is an effective down-regulator of EZH2 via proteasome-mediated degradation. NSC745885 is also an effective anti-tumor agent that displays selective toxicity against multiple cancer cell lines but not normal cel...
T60659 Cdc7-IN-12
Cdc7-IN-12 (compound 1) is a potent inhibitor of CDC7 (IC 50 of <1 nM) that has the potential in the cancer research. Cdc7-IN-12 exhibits antiproliferative activities in COLO205 cells with IC 50 of 100-1000 nM [1].
T60815 Cdc7-IN-9
Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].
T62231 Cdc7-IN-11
Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases.
T78423 ARC7
ARC7 serves as a probe for investigating secondary metabolism and the streptomycete life cycle in S. coelicolor, offering insights into the organism's complex biochemical processes [1].
T75168 Homo-BacPROTAC7
Homo-BacPROTAC7, a ClpC1 NTD BacPROTAC degrader, targets ClpC2 and efficiently kills M. tuberculosis [1].
T78271 Anti-Mouse TCR gamma/delta Antibody (UC7-13D5)
Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.

Compounds

Pomalidomide-C7-NH2 hydrochloride
T40004
Synonym:
Target: Others
Pomalidomide-C7-COOH
T39701
Synonym: Pomalidomide-C7-COOH
Target:
Thalidomide-O-C7-NH2
T39511
Synonym: Thalidomide-O-C7-NH2
Target:
Thalidomide-O-C7-acid
T39645
Synonym: Thalidomide-O-C7-acid
Target:
(S,R,S)-AHPC-C7-amine
T39838
Synonym: VH032-C7-amine,(S,R,S)-AHPC-C7-amine
Target:
AP-C7
T82988
Synonym:
Target:
(S,R,S)-AHPC-Me-C7 ester
T18671
Synonym:
Target: Others
Thalidomide-4-O-C7-NH2 hydrochloride
T77917
Synonym:
Target:
Thalidomide-5-O-C7-NH2 hydrochloride
T77954
Synonym:
Target:
VH 032 amide-alkylC7-acid
T83954
Synonym: (S,R,S)-AHPC-amido-C7-acid
Target:
Triheptanoin
T19663
Synonym: UX 007,IND106011,UX007,UX-007,IND 106011,IND-106011
Target: Others
Cdc7-IN-5
T10727
Synonym:
Target: CDK
LDC7559
T11828
Synonym:
Target: Pyroptosis
GC7 Sulfate
T11372
Synonym:
Target: Autophagy
Compound C749
T50125
Synonym:
Target:
Cdc7-IN-7c
T23867
Synonym: Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c
Target: CDK
KDM5-C70
T15648
Synonym:
Target: Histone Demethylase
NSC781406
T16355
Synonym:
Target: PI3K, mTOR
SC79
T2274
Synonym: SC 79
Target: Akt
NSC756093
T24557
Synonym: NSC-756093,NSC 756093
Target: Others
trans-C75
T10656
Synonym: (±)-C75
Target: Others, Fatty Acid Synthase
C75
T10657
Synonym: C-75
Target: Fatty Acid Synthase
NVP-ACC789
T3463
Synonym: ACC-789,ZK202650
Target: VEGFR, PDGFR
ZINC77292789
TP1166
Synonym: Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH
Target: Others
UNC7467
T60164
Synonym:
Target: Others
SC75741
T6661
Synonym:
Target: Influenza Virus, NF-κB
Cdc7-IN-7
T10729
Synonym:
Target: CDK
AC710
TQ0235
Synonym:
Target: FLT, PDGFR, c-Kit
SGC707
T3084
Synonym:
Target: Histone Methyltransferase
KC7F2
T3169
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, HIF
EBNA1-IN-SC7
T62921
Synonym:
Target:
Cdc7-IN-14
T61289
Synonym:
Target:
VH 032 amide-alkylC7-amine
T36282
Synonym: VH 032 amide-alkylC7-amine
Target:
(S)-Cdc7-IN-18
T61435
Synonym:
Target:
HD-TAC7
T74514
Synonym:
Target:
Cdc7-IN-13
T61288
Synonym:
Target:
PhosTAC7
T77934
Synonym:
Target: PROTACs
UNC7096
T79616
Synonym:
Target: Histone Methyltransferase
Cdc7-IN-19
T61223
Synonym:
Target:
Cdc7-IN-1
T10724
Synonym:
Target: CDK
JCC76
T71597
Synonym:
Target:
Cdc7-IN-18
T61436
Synonym:
Target:
Cdc7-IN-17
T60589
Synonym:
Target:
NSC745885
T16354
Synonym:
Target: Others
Cdc7-IN-12
T60659
Synonym:
Target:
Cdc7-IN-9
T60815
Synonym:
Target:
Cdc7-IN-11
T62231
Synonym:
Target:
ARC7
T78423
Synonym:
Target:
Homo-BacPROTAC7
T75168
Synonym:
Target:
Anti-Mouse TCR gamma/delta Antibody (UC7-13D5)
T78271
Synonym:
Target:
1 2

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-03012 Complement C7 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Complement C7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 118 kDa and the accession number is P10643.
TMPY-02892 Complement C7 Protein, Human, Recombinant (His) Human HEK293 Cells
Complement C7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 92.6 kDa and the accession number is P10643.
TMPY-02970 CXCL10 Protein, Human, Recombinant Human E. coli
CXCL10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is P02778.
TMPK-01269 CXCL10 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothel...
TMPH-03750 SLC7A11 Protein, Human, Recombinant (His) Human E. coli
Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
TMPY-04061 HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) HIV E. coli
HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 58.8 kDa and the accession number is L8B302...
TMPH-01604 SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 19.7 kDa and the accession number is Q01650.
TMPH-01475 HDAC7 Protein, Human, Recombinant (His) Human E. coli
N/A. HDAC7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26 kDa and the accession number is Q8WUI4 (BC064840).
TMPY-04118 Livin/BIRC7 Protein, Human, Recombinant (His) Human E. coli
BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is...
TMPH-02528 SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar) Mouse P. pastoris (Yeast)
Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the ...
TMPK-01049 CLEC7A Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis...
TMPY-02217 HSC70 Protein, Human, Recombinant (His) Human E. coli
HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed m...
TMPH-00218 DHCR7 Protein, Bovine, Recombinant (His) Bovine E. coli
7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in th...
TargetMol