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Cat No. | Product Name | Synonyms | Targets |
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T40004 | Pomalidomide-C7-NH2 hydrochloride | Others | |
Pomalidomide-C7-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology. | |||
T39701 | Pomalidomide-C7-COOH | Pomalidomide-C7-COOH | |
Pomalidomide-C7-COOH is a chemically synthesized E3 ligase cereblon ligand-linker conjugate, utilized as an intermediate compound for the synthesis of PROTAC BCL-XL degraders. | |||
T39511 | Thalidomide-O-C7-NH2 | Thalidomide-O-C7-NH2 | |
Thalidomide-O-C7-NH2 is a synthesized conjugate compound comprising an E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Thalidomide and a linker that is commonly employed in PROTAC... | |||
T39645 | Thalidomide-O-C7-acid | Thalidomide-O-C7-acid | |
Thalidomide-O-C7-acid is a compound created through the synthesis of an E3 ligase ligand-linker conjugate. It consists of a cereblon ligand derived from Thalidomide, combined with a linker that is commonly employed in PR... | |||
T39838 | (S,R,S)-AHPC-C7-amine | VH032-C7-amine,(S,R,S)-AHPC-C7-amine | |
(S,R,S)-AHPC-C7-amine, also known as VH032-C7-amine, is a chemically synthesized conjugate that functions as an E3 ligase ligand-linker. This compound combines the VH032-based VHL ligand with a specific linker designed f... | |||
T82988 | AP-C7 | ||
AP-C7 is a selective inhibitor of cGMP-dependent protein kinase II (cGKII) with a pIC50 value of 5.0, demonstrating only weak inhibition of cGKII-dependent anion secretion [1]. | |||
T18671 | (S,R,S)-AHPC-Me-C7 ester | Others | |
(S,R,S)-AHPC-Me-C7 ester is a E3 ligase ligand-linker conjugate used to synthesise BCL-XL PROTAC degraders[1]. | |||
T77917 | Thalidomide-4-O-C7-NH2 hydrochloride | ||
Thalidomide-4-O-C7-NH2 hydrochloride, a Thalidomide-based cereblon ligand, plays a role in the recruitment of CRBN protein and, when linked to a protein ligand, forms PROTACs [1]. | |||
T77954 | Thalidomide-5-O-C7-NH2 hydrochloride | ||
Thalidomide-5-O-C7-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates CRBN protein recruitment. This compound can be tethered to a protein-targeting ligand using a linker, enabling the formation of PROTA... | |||
T83954 | VH 032 amide-alkylC7-acid | (S,R,S)-AHPC-amido-C7-acid | |
VH 032 amide-alkylC7-acid is a specialized compound designed for PROTAC research and development, serving as a functionalized von-Hippel-Lindau (VHL) protein ligand. It combines an E3 ligase ligand with an alkylC7 linker... | |||
T19663 | Triheptanoin | UX 007,IND106011,UX007,UX-007,IND 106011,IND-106011 | Others |
Triheptanoin (IND 106011) is a fatty acid metabolic modulator. It potentially for the treatment of fatty acid oxidation disorders and GLUT1. | |||
T10727 | Cdc7-IN-5 | CDK | |
Cdc7-IN-5 is a potent inhibitor of Cdc7 kinase. Cdc7, a serine-threonine protein kinase enzyme, is essential for the initiation of DNA replication in the cell cycle. | |||
T11828 | LDC7559 | Pyroptosis | |
LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage. | |||
T11372 | GC7 Sulfate | Autophagy | |
GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS act... | |||
T50125 | Compound C749 | ||
Compound C749 is a useful organic compound for research related to life sciences. The catalog number is T50125 and the CAS number is 57-03-4. | |||
T23867 | Cdc7-IN-7c | Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c | CDK |
Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer. | |||
T15648 | KDM5-C70 | Histone Demethylase | |
KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide e... | |||
T16355 | NSC781406 | PI3K , mTOR | |
NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα). | |||
T2274 | SC79 | SC 79 | Akt |
SC79 is an AKT agonist with specificity and blood-brain barrier permeability. SC79 specifically binds to the PH domain of AKT, activates cytoplasmic AKT, and inhibits AKT membrane translocation. SC79 has neuroprotective ... | |||
T24557 | NSC756093 | NSC-756093,NSC 756093 | Others |
NSC756093 potentially inhibits GBP1:PIM1 interaction. NSC756093 can be used in ovarian cancer studies. | |||
T10656 | Trans-C75 | (±)-C75 | Others , Fatty Acid Synthase |
trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN). | |||
T10657 | C75 | C-75 | Fatty Acid Synthase |
C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM). | |||
T3463 | NVP-ACC789 | ACC-789,ZK202650 | VEGFR , PDGFR |
ACC-789 (NVP-ACC789 (ZK202650); ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases. | |||
TP1166 | ZINC77292789 | Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH | Others |
ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC7729... | |||
T60164 | UNC7467 | Others | |
UNC7467 is a potent IP6K inhibitor with values of 4.9, 8.9 and 1320 nM for IP6K2, IP6K1 and IP6K6, respectively. UNC7467 reduces levels of inositol pyrophosphates without significantly perturbing levels of other inositol... | |||
T6661 | SC75741 | Influenza Virus , NF-κB | |
SC75741 is a potent P65 inhibitor with IC50 of 200 nM | |||
T10729 | Cdc7-IN-7 | CDK | |
Cdc7-IN-7 is a potent inhibitor of Cdc7 kinase. | |||
TQ0235 | AC710 | FLT , PDGFR , c-Kit | |
AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ). | |||
T3084 | SGC707 | Histone Methyltransferase | |
SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3. | |||
T3169 | KC7F2 | HIF/HIF Prolyl-Hydroxylase , HIF | |
KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity. | |||
T62921 | EBNA1-IN-SC7 | ||
EBNA1-IN-SC7 (compound SC7) is a selective inhibitor of Epstein-Barr nuclear antigen 1 (EBNA1) that interferes with EBNA1-DNA binding activity (IC50: 23 μM). Barr virus (EBV) related cancers. | |||
T61289 | Cdc7-IN-14 | ||
Cdc7-IN-14 (compound 82) is a highly potent inhibitor of CDC7, demonstrating an IC50 value of less than 1 nM. This compound, Cdc7-IN-14, exhibits promising potential for cancer research [1]. | |||
T36282 | VH 032 amide-alkylC7-amine | VH 032 amide-alkylC7-amine | |
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of funct... | |||
T61435 | (S)-Cdc7-IN-18 | ||
(S)-Cdc7-IN-18, a potent CDC7 inhibitor, effectively impedes the overactivation of MCM2, a crucial tumor cell marker, induced by huCdc7 overexpression. Consequently, it inhibits the aberrant proliferation of tumor cells.... | |||
T74514 | HD-TAC7 | ||
HD-TAC7, a potent PROTAC HDAC degrader, exhibits IC50 values of 3.6 μM, 4.2 μM, and 1.1 μM for HDAC1, HDAC2, and HDAC3, respectively. It effectively decreases NF-κB p65 in RAW 264.7 macrophages and is utilized in researc... | |||
T61288 | Cdc7-IN-13 | ||
Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1]. | |||
T77934 | PhosTAC7 | PROTACs | |
PhosTAC7, akin to PROTACs in promoting ternary complex formation, recruits a Ser/Thr phosphatase to a phosphosubstrate to facilitate dephosphorylation. | |||
T79616 | UNC7096 | Histone Methyltransferase | |
UNC7096 is a potent, selective degrader of NSD2-PWWP1, exhibiting a dissociation constant (Kd) of 46 nM, and shows promise for treating NSD2-related diseases [1]. | |||
T61223 | Cdc7-IN-19 | ||
Cdc7-IN-19 (compound 1-1) is a potent CDC7 inhibitor with an IC 50 of 1.49 nM [1]. | |||
T10724 | Cdc7-IN-1 | CDK | |
Cdc7-IN-1 is a highly selective and ATP competitive inhibitor of Cdc7 kinase (IC50: 0.6 nM at 1 mM ATP). It potently inhibits Cdc7 activity in cancer cells and effectively induces cell death. | |||
T71597 | JCC76 | ||
JCC76 is a selective inhibitor of heat shock protein 27 (Hsp27). JCC76 inhibits the proliferation of human epidermal growth factor 2 (Her2). | |||
T61436 | Cdc7-IN-18 | ||
Cdc7-IN-18 (compound 1-2) is a highly effective inhibitor of the CDC7 enzyme. It has an IC 50 value of 1.29 nM for the Cdc7/DBF4 enzyme. In addition, this compound exhibits strong antiproliferative activities, with an IC... | |||
T60589 | Cdc7-IN-17 | ||
Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1]. | |||
T16354 | NSC745885 | Others | |
NSC745885 is an effective down-regulator of EZH2 via proteasome-mediated degradation. NSC745885 is also an effective anti-tumor agent that displays selective toxicity against multiple cancer cell lines but not normal cel... | |||
T60659 | Cdc7-IN-12 | ||
Cdc7-IN-12 (compound 1) is a potent inhibitor of CDC7 (IC 50 of <1 nM) that has the potential in the cancer research. Cdc7-IN-12 exhibits antiproliferative activities in COLO205 cells with IC 50 of 100-1000 nM [1]. | |||
T60815 | Cdc7-IN-9 | ||
Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1]. | |||
T62231 | Cdc7-IN-11 | ||
Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases. | |||
T78423 | ARC7 | ||
ARC7 serves as a probe for investigating secondary metabolism and the streptomycete life cycle in S. coelicolor, offering insights into the organism's complex biochemical processes [1]. | |||
T75168 | Homo-BacPROTAC7 | ||
Homo-BacPROTAC7, a ClpC1 NTD BacPROTAC degrader, targets ClpC2 and efficiently kills M. tuberculosis [1]. | |||
T78271 | Anti-Mouse TCR gamma/delta Antibody (UC7-13D5) | ||
Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03012 | Complement C7 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Complement C7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 118 kDa and the accession number is P10643. | |||
TMPY-02892 | Complement C7 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Complement C7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 92.6 kDa and the accession number is P10643. | |||
TMPY-02970 | CXCL10 Protein, Human, Recombinant | Human | E. coli |
CXCL10 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.8 kDa and the accession number is P02778. | |||
TMPK-01269 | CXCL10 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
C-X-C motif ligand 10 (CXCL10), or interferon-inducible protein-10, is a small chemokine belonging to the CXC chemokine family. Its members are responsible for leukocyte trafficking and act on tissue cells, like endothel... | |||
TMPH-03750 | SLC7A11 Protein, Human, Recombinant (His) | Human | E. coli |
Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. | |||
TMPY-04061 | HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) | HIV | E. coli |
HIV-2 (subtype CRF01_AB, strain 07JP_NMC716_clone_01) gp36 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 58.8 kDa and the accession number is L8B302... | |||
TMPH-01604 | SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
SLC7A5 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 19.7 kDa and the accession number is Q01650. | |||
TMPH-01475 | HDAC7 Protein, Human, Recombinant (His) | Human | E. coli |
N/A. HDAC7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26 kDa and the accession number is Q8WUI4 (BC064840). | |||
TMPY-04118 | Livin/BIRC7 Protein, Human, Recombinant (His) | Human | E. coli |
BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is... | |||
TMPH-02528 | SLC7A10 Protein, Mouse, Recombinant (His & SUMOstar) | Mouse | P. pastoris (Yeast) |
Sodium-independent, high affinity transport of small neutral D- and L-amino acids and amino acid-related compounds. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the ... | |||
TMPK-01049 | CLEC7A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis... | |||
TMPY-02217 | HSC70 Protein, Human, Recombinant (His) | Human | E. coli |
HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed m... | |||
TMPH-00218 | DHCR7 Protein, Bovine, Recombinant (His) | Bovine | E. coli |
7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in th... |