Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 72.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 328.00 | |
25 mg | In stock | $ 558.00 | |
50 mg | In stock | $ 788.00 | |
100 mg | In stock | $ 1,120.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 226.00 |
Description | LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage. |
In vitro | LDC7559 (1 and 5 μM) inhibits IL-1β release upon inflammasome activation, and significantly blocks the lethal effect of both human and murine GSDMD NT domains transfected into HEK293T cells[3]. |
Molecular Weight | 349.38 |
Formula | C20H19N3O3 |
CAS No. | 2407782-01-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (271.91 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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LDC7559 2407782-01-6 Apoptosis Immunology/Inflammation Pyroptosis Inhibitor inhibit LDC 7559 LDC-7559 inhibitor