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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16695 | Pyrintegrin | Integrin | |
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal... | |||
T21955 | GQ-16 | PPAR | |
GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain. | |||
T8740 | COH-SR4 | COH-SR4 (Mitochondria uncoupler SR4) | Others , AMPK |
COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation. COH-SR4 modulates amp-dependent kinase (ampk)-mammalian target of rapamycin (mtor) signaling, and inhibiting proli... | |||
T4S1173 | Agrimol B | Sirtuin , PPAR | |
1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb. | |||
T3739 | 2,6-Dimethoxyquinone | 2,6-Dimethoxy-1,4-benzoquinone,2,6-Dimethoxy-p-benzoquinone,2,6-Dimethoxybenzoquinone | Others |
2,6-Dimethoxyquinone (2,6-Dimethoxy-p-benzoquinone) is a member of the class of compounds known as P-benzoquinones. 2,6-Dimethoxyquinone is slightly soluble (in water) and an extremely weak basic (essentially neutral) co... | |||
T2882 | Genistin | Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside | Apoptosis , Estrogen Receptor/ERR , Others |
Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities | |||
TN1836 | Kudinoside D | LDL , AMPK , PPAR | |
Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway. | |||
TN1803 | Isoscoparin | Antioxidant , TNF , NO Synthase , Fatty Acid Synthase | |
Isoscoparin is derived from Gentiana algida Pall with antioxidant and anti-adipogenic activities. Isoscoparin can be used in stuides about the prevention and treatment of obesity. | |||
TN1189 | 13-Methylberberine chloride | 13-Methylberberine | Others |
13-Methylberberine chloride shows anti-adipogenic effect on 3T3-L1 adipocytes, it has potential as an anti-obesity drug | |||
T1866 | AT-56 | Others , PGE Synthase | |
AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects. | |||
T67855 | ISX-3 | Others | |
ISX-3 is a potent pro-osteogenic and anti-adipogenic agent. ISX-3 can increase the expression of PPARγ. ISX-3 can be for the research of osteopenia and osteoporosis. | |||
T8184 | Fucosterol | PARP , Endogenous Metabolite , PPAR | |
Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression. | |||
T2S0410 | Euphorbia factor L1 | Euphorbiasteroid | Apoptosis , P-gp |
Euphorbia factor L1 (Euphorbiasteroid) can reduce Bcl-2, PI3K, AKT, and mTOR protein and mRNA levels, and up-regulate caspase-9 and caspase-3 protein levels. It induces autophagy and has anti-cancer, anti-adipogenic, ant... | |||
T5S2361 | Epiberberine | ERK , Beta-Secretase , MEK , BACE , AMPK , AChR , AChE | |
1. Epiberberine may be caused drug interactions based on CYP2D6 enzyme. 2. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKα/Akt pathways during 3T3-L1 adipocyte diffe... | |||
T69015 | THR-0921 | ||
THR-0921 is a peroxisome proliferator-activated gamma (PPAR gamma) agonist that has antihyperglycemic activity with low adipogenic potential. | |||
T12828 | Salicortin | NF-κB , JNK | |
Salicortin is a phenolic glycoside isolated from many plants such as Populus and Salix species, has anti-adipogenic, anti-amnesic, and immune-modulatory activity. | |||
T13205 | Triphala | Others | |
Triphala is an Ayurvedic polyherbal formulation. Triphala inhibits NF-κB activation. Triphala exerts antifungal action, and with anti-adipogenic, anti-inflammatory, and antineoplastic activities. | |||
TN2896 | 3,5-Dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane | Others | |
(3R,5R)-3,5-dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)-heptane may have anti-adipogenic activity. | |||
TN4092 | Galanolactone | 5-HT Receptor | |
Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with IC(50) values ranging from 5.5 to 28.5 μM. Galanolactone ex... | |||
TN2228 | Soyasaponin Aa | PPAR | |
Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the downregulation of the adipogenesis-related transcription factor... |