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Genistin
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Catalog No. T2882Cas No. 529-59-9
Alias Genistoside, Genistine, Genistein glucoside, Genistein 7-O-β-D-glucopyranoside, Genistein 7-glucoside
Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities
Genistin
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Purity: 97.85%
Catalog No. T2882Alias Genistoside, Genistine, Genistein glucoside, Genistein 7-O-β-D-glucopyranoside, Genistein 7-glucosideCas No. 529-59-9
Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $32 | In Stock | In Stock | |
| 10 mg | $43 | In Stock | In Stock | |
| 25 mg | $65 | In Stock | In Stock | |
| 50 mg | $71 | In Stock | In Stock | |
| 100 mg | $98 | In Stock | In Stock | |
| 500 mg | $242 | In Stock | In Stock | |
| 1 mL x 10 mM (in DMSO) | $48 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:97.85%
Appearance:Solid
Color:White
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Product Introduction
Genistin AI Summary
Genistin demonstrates a diverse range of bioactivities. It shows inhibitory activity against cow milk xanthine oxidase at 50 µg/mL, with an inhibition rate of 0.8%. In human A431 cells, it inhibits EGFR with an IC50 greater than 100.0 µg/mL. The compound also exhibits moderate to high antioxidant capacities, including ABTS and DPPH radical scavenging activities, and activities assessed through the TEAC and MTT assays, with significant findings including a deltaA value of 0.33 and a strong ability to scavenge AAPH-induced peroxyl radicals at 10 µM in the oxygen radical absorbance assay.
Furthermore, Genistin inhibits acetylcholinesterase (AChE) from electric eels by 24.63% at 2 mg/mL, while showing a lower inhibition rate of 1.82% on butyrylcholinesterase (BChE) from horses. It also has potential as an inhibitor for the Marburg Virus, demonstrating a potency of 4466.8 nM. However, it exhibits no significant antifungal or antibacterial activities against Candida albicans, Cryptococcus neoformans, Escherichia coli, and Staphylococcus aureus at MIC > 100.0 µg/mL.
Genistin inhibits LPS-induced nitric oxide production in mouse RAW264.7 cells with an IC50 value greater than 1000.0 nM, indicating moderate to weak activity. It displays significant binding affinity and displacement of thiazole orange from various DNA structures, including G4 quadruplex and i-motif DNA, with notable impact on DNA melting temperatures under different conditions..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities |
| Synonyms | Genistoside, Genistine, Genistein glucoside, Genistein 7-O-β-D-glucopyranoside, Genistein 7-glucoside |
| Molecular Weight | 432.38 |
| Formula | C21H20O10 |
| Cas No. | 529-59-9 |
| Smiles | OC[C@H]1O[C@@H](Oc2cc(O)c3c(c2)occ(-c2ccc(O)cc2)c3=O)[C@H](O)[C@@H](O)[C@@H]1O |
| Relative Density. | 1.642 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 32 mg/mL (74.01 mM), Sonication is recommended. DMSO: 250 mg/mL (578.2 mM), Sonication is recommended.  H2O: < 1 mg/mL (insoluble or slightly soluble) | ||||||||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.63 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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