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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TMS2171 | (±)-Naringenin | Salipurpol,Naringenine,Naringenin | Potassium Channel |
(±)-Naringenin (Naringenine) is a natural product. It displays vasorelaxant effect on endothelium-denuded vessels via the activation of BKCa channels in myocytes. | |||
T9133 | Caroverine hydrochloride | Caroverine HCL | GluR , NMDAR , iGluR |
Caroverine hydrochloride (Caroverine HCL) is a potent, competitive and reversible antagonist of NMDA and AMPA glutamate receptor. It is also an antioxidant and calcium-blocking agent that exhibits vasorelaxant action, an... | |||
TN2290 | Uvaol | Endogenous Metabolite , JNK , PPAR | |
Uvaol is present in olives and virgin olive oil with anti-inflammatory, anti-proliferative, and vasorelaxant activities. | |||
TN1121 | Evocarpine | Apoptosis , cAMP , Anti-infection , Calcium Channel , Antibacterial | |
Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels. | |||
T5552 | Methyl cinnamate | Tyrosinase , Antibacterial , AMPK | |
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects. | |||
TN1416 | Ayanin | IL Receptor , P450 , PARP , PDE | |
Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 productio... | |||
TN1624 | Ethyl cinnamate | Calcium Channel , ROS , NO Synthase | |
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl... | |||
T4001 | Euxanthone | 1,7-Dihydroxyxanthone | Autophagy |
Euxanthone (1,7-Dihydroxyxanthone), an xanthone derivative extracted from the roots of Polygala tenuifolia Willd, has antitumour, neuroprotective and vasorelaxant activities, and attenuates Aβ1-42-induced oxidative stres... | |||
TN1724 | Harmalol hydrochloride | Harmidol hydrochloride | P450 , Antioxidant |
Harmalol hydrochloride (Harmidol hydrochloride) is a β-carboline alkaloid that can be extracted from the seeds of Peganum harmala L. Harmalol hydrochloride is the major metabolite of Harmaline and significantly inhibits ... | |||
TN6519 | Saucerneol | ||
Saucerneol has significant cardiovascular effects such as vasorelaxant and negative inotropic actions. | |||
T13341 | Win 58237 | Others | |
Win 58237 is an inhibitor of cyclic nucleotide phosphodiesterase (PDE) (Ki: 170 nM for PDE V), with vasorelaxant activity. | |||
T83596 | (+)-Osbeckic acid | ||
(+)-Osbeckic acid, extracted from Tartary Buckwheat, acts as a vasorelaxant and demonstrates a significant vasorelaxant effect in Sprague-Dawley rat thoracic aorta rings, with an EC50 value of 887 μM [1]. | |||
T72001 | CB096 | ||
CB096 is a novel inhibitor of RAN translation. specifically binds to a repeating 1 × 1 GG internal loop structure, 5'CGG/3'GGC, that is formed when r(G4C2)exp folds, also acting as a potent vasorelaxant agent, showing an... | |||
T80867 | Villocarine A | ||
Villocarine A, an indole alkaloid with natural vasorelaxant properties [1], is a chemical compound known for its ability to relax blood vessels. | |||
T76386 | ANP (1-30), frog | ||
ANP (1-30), frog, a peptide fragment sourced from atrial natriuretic peptide of frog origin, exhibits natriuretic, diuretic, and vasorelaxant properties. | |||
T27436 | GS 389 | GS-389,GS389 | |
GS 389 is a novel tetrahydroisoquinoline analog with vasorelaxant properties. GS-389 significantly inhibited cGMP phosphodiesterase from the rabbit brain and increased cGMP levels in the rat aorta. | |||
T74579 | Ferulic acid 4-O-sulfate | ||
Ferulic Acid 4-O-Sulfate (Ferulic Acid 4-Sulfate), a metabolite of Ferulic Acid, demonstrates vasorelaxant properties and reduces blood pressure in mice [1]. | |||
TN2918 | 3-Acetoxy-8(17),13E-labdadien-15-oic acid | cAMP , Potassium Channel , Calcium Channel | |
ent-3-Acetoxy-labda-8(17),13-dien-15-oic acid have vasorelaxant and hypotensive actions, the mechanisms underlying the cardiovascular actions of the labdane involve the activation of the endothelial NO-cGMP pathway, the ... | |||
TN1503 | Cistanoside F | NADPH-oxidase | |
Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide ani... | |||
TN5147 | Tilifodiolide | IL Receptor , TNF , GABA Receptor | |
Tilifodiolide exerts in vitro and in vivo anti-inflammatory activity and in vivo antinociceptive effects. Tilifodiolide exerted antidiarrheal activity by decreasing the intestinal fluid accumulation and vasorelaxant effe... |