vasodilation — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15130	Dilazep dihydrochloride		Others
	Dilazep dihydrochloride is an adenosine uptake inhibitor. It also inhibits ischemic damage, membrane transport of nucleosides, and platelet aggregation. It has cerebral and coronary vasodilating action through the enhanc...		Others
T11831	LDN-27219		Others
	LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.		Others
T1626	Prostaglandin E1	PGE1,Alprostadil	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...		Endogenous Metabolite , Prostaglandin Receptor
T6835	Fenoldopam mesylate	Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526	Dopamine Receptor
	Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.		Dopamine Receptor
T16669	PRX-08066		5-HT Receptor
	PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.		5-HT Receptor
T4661	PKG drug G1		PKA
	PKG drug G1 targets PKG Iα C42. PKG drug G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.		PKA
TN7254	(E,E)-Farnesol	(2E,6E)-Farnesol	Others
	(E,E)-Farnesol ((2E,6E)-Farnesol) is a sesquiterpene acyclic alcohol produced by bacteria, protozoa, fungi, plants, and animals. (E,E)-Farnesol promotes vasodilation.		Others
T10631	Bucindolol	BMY 13105,MJ 131051,MJ 13105	Adrenergic Receptor
	Bucindolol (BMY 13105) is a novel and potent β1-adrenergic receptor blocker that mediates vasodilation and can be used to study chronic heart failure.		Adrenergic Receptor
T3216	Selexipag	NS-304,ACT-293987,Uptravi	Others , Prostaglandin Receptor
	Selexipag (ACT-293987)(NS-304) is prostacyclin receptor agonist that causes vasodilation in pulmonary vasculature and is used in the therapy of pulmonary arterial hypertension (PAH).		Others , Prostaglandin Receptor
T38248	2-Ethylpyrazine		Endogenous Metabolite , NO Synthase
	2-Ethylpyrazine is present in roasted coffee beans and is a volatile compound .2-Ethylpyrazine induces vasodilation through the activity of endothelium-derived relaxing factors.2-Ethylpyrazine activates NO synthesis thro...		Endogenous Metabolite , NO Synthase
T5562	Methyl nicotinate	methyl pyridine-3-carboxylate	Others
	Methyl nicotinate (methyl pyridine-3-carboxylate) is the methyl ester of that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of m...		Others
T20793	Magnesium Lithospermate B	Monomethyl lithospermate B,Lithospermate B	Others
	Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is...		Others
TP1016L	Aviptadil Acetate	Vasoactive Intestinal Peptide acetate salt	RAAS , SARS-CoV
	Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for research on pulmona...		RAAS , SARS-CoV
T2520	Desloratadine	Sch34117,NSC 675447	Endogenous Metabolite , Histamine Receptor
	Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smoot...		Endogenous Metabolite , Histamine Receptor
T23356	Linsidomine hydrochloride	SIN-1 chloride	Others
	Linsidomine hydrochloride (SIN-1 chloride) is considered as a metabolite of moxidomine, with vasodilation, inhibition of platelet aggregation, and antiangina activity. In myocardial ischemia-reperfusion models, Linsidomi...		Others
T5979	1-beta-D-Arabinofuranosyluracil	Uracil 1-β-D-arabinofuranoside	Others
	1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has anti-inflammatory activity, an...		Others
T1398	Tadalafil	Cialis,IC-351	Apoptosis , PDE
	Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGM...		Apoptosis , PDE
T27753	KT-362 fumarate	KT 362,KT362,KT-362	Potassium Channel , Calcium Channel , Sodium Channel
	KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by affecting intracellular calcium mobilization in atrial mus...		Potassium Channel , Calcium Channel , Sodium Channel
T34698	Spongosine	2-Methoxy adenosine	Others
	Spongosine (2-Methoxy adenosine) is a pivotal intercellular signal transmitter, which has demonstrated a diverse bioactivity profile including anti-inflammatory activity and analgesic and vasodilation properties. Spongos...		Others
T63349	Treprostinil diethanolamine	UT-15C	Prostaglandin Receptor
	Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FPKi, respectively. Treprostinil diethanolamine i...		Prostaglandin Receptor