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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4132 | BPTU | BMS-646786 | P2Y Receptor |
BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced... | |||
T1891 | NSC 405020 | MMP | |
NSC 405020 is a noncatalytic inhibitor of MT1-MMP. | |||
T2629 | UNC2881 | TAM Receptor | |
UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively. | |||
T4S0592 | Toddalolactone | (+)-Toddalolactone | PAI-1 |
Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic. | |||
T4978 | Sarpogrelate hydrochloride | MCI-9042 | 5-HT Receptor |
Sarpogrelate hydrochloride (MCI-9042) , a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at ... | |||
T2223 | Kinetin | 6-Furfuryladenine,N6-Furfuryladenine | Others |
Kinetin (N6-Furfuryladenine), a type of cytokinin, has plant growth regulation effects. | |||
T4570 | Pipobroman | Vercyte,A-8103,Amedel | Others , DNA Alkylator/Crosslinker |
Pipobroman (Vercyte) is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemia (ET). Pipobroman allows, wit... | |||
T12870 | SCH79797 dihydrochloride | Apoptosis , Others , Protease-activated Receptor | |
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects. | |||
T0005 | Aspirin | Acetylsalicylate,Acetylsalicylic Acid,ASA | Mitophagy , Virus Protease , COX , Autophagy |
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel... | |||
T34280 | Regrelor disodium | INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589 | P2Y Receptor |
Regrelor disodium (INS 50589) is a p2y12 receptor antagonist that prevents thrombosis, effectively inhibits vascular smooth muscle cell contraction, inhibits cell proliferation, and reduces inflammation. | |||
T35161 | Xemilofiban | SC-54684A,SC54684A,SC 54684A | Others |
Xemilofiban (SC 54684A) interrupts platelet aggregation, promotes thrombosis, and is used in the study of unstable angina. | |||
T24567 | Octimibate | Octimibato | Prostaglandin Receptor |
Octimibate (Octimibato) is a non-prostaglandin platelet aggregation inhibitor and cyclic prostaglandin agonist.Octimibate is used in the treatment of cardiovascular disease and can be used to study atherosclerosis and th... | |||
T3469 | PCI-27483 | PCI27483 | Others |
PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg... | |||
T80792 | WAY-639228 | Others | |
WAY-639228-A has potential antithrombotic and anticoagulant activity for the study of cerebral thrombosis. | |||
T27630 | Isbogrel | CV4151,CV-4151,CV 4151 | Prostaglandin Receptor |
Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks and thrombosis. | |||
T2S0007 | Ferulic acid sodium | Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate | FGFR , Reactive Oxygen Species , 5-HT Receptor , Endogenous Metabolite |
Ferulic acid sodium (Sodium ferulic), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis. | |||
T68022L | Sulotroban potassium | BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base) | PPAR |
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis. | |||
T68078 | Gantofiban | Integrin | |
Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis. | |||
T29215 | Zifaxaban | TY 602,TY602,TY-602 | Factor Xa |
Zifaxaban (TY-602) is an orally active, competitive and selective inhibitor of factor Xa (FXa) with an IC50 of 11.1 nM for human FXa.Zifaxaban has a very high affinity, more than 10,000-fold higher than that of other ser... | |||
T6952 | Prasugrel Hydrochloride | LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl | P2Y Receptor |
Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome. |