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Search Results for " thrombosis "

20

Compounds

Cat No. Product Name Synonyms Targets
T4132 BPTU BMS-646786 P2Y Receptor
BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced...
T1891 NSC 405020 MMP
NSC 405020 is a noncatalytic inhibitor of MT1-MMP.
T2629 UNC2881 TAM Receptor
UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.
T4S0592 Toddalolactone (+)-Toddalolactone PAI-1
Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.
T4978 Sarpogrelate hydrochloride MCI-9042 5-HT Receptor
Sarpogrelate hydrochloride (MCI-9042) , a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at ...
T2223 Kinetin 6-Furfuryladenine,N6-Furfuryladenine Others
Kinetin (N6-Furfuryladenine), a type of cytokinin, has plant growth regulation effects.
T4570 Pipobroman Vercyte,A-8103,Amedel Others , DNA Alkylator/Crosslinker
Pipobroman (Vercyte) is an anti-cancer drug that probably acts as an alkylating agent. Pipobroman has well documented clinical activity in polycythemia vera (PV) and essential thrombocythemia (ET). Pipobroman allows, wit...
T12870 SCH79797 dihydrochloride Apoptosis , Others , Protease-activated Receptor
SCH79797 dihydrochloride is an effective and selective antagonist of protease activated receptor 1 (PAR1) with an IC50 of 70 nM and a Ki of 35 nM. SCH79797 dihydrochloride has antiproliferative and pro-apoptotic effects.
T0005 Aspirin Acetylsalicylate,Acetylsalicylic Acid,ASA Mitophagy , Virus Protease , COX , Autophagy
Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...
T34280 Regrelor disodium INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589 P2Y Receptor
Regrelor disodium (INS 50589) is a p2y12 receptor antagonist that prevents thrombosis, effectively inhibits vascular smooth muscle cell contraction, inhibits cell proliferation, and reduces inflammation.
T35161 Xemilofiban SC-54684A,SC54684A,SC 54684A Others
Xemilofiban (SC 54684A) interrupts platelet aggregation, promotes thrombosis, and is used in the study of unstable angina.
T24567 Octimibate Octimibato Prostaglandin Receptor
Octimibate (Octimibato) is a non-prostaglandin platelet aggregation inhibitor and cyclic prostaglandin agonist.Octimibate is used in the treatment of cardiovascular disease and can be used to study atherosclerosis and th...
T3469 PCI-27483 PCI27483 Others
PCI-27483 is an activated coagulation factor VIIa inhibitor with antithrombotic effects in a baboon model of arterial thrombosis. It also inhibits the growth of BxPC3 xenografts by 42% and 85% at doses of 60 and 90 mg/kg...
T80792 WAY-639228 Others
WAY-639228-A has potential antithrombotic and anticoagulant activity for the study of cerebral thrombosis.
T27630 Isbogrel CV4151,CV-4151,CV 4151 Prostaglandin Receptor
Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks and thrombosis.
T2S0007 Ferulic acid sodium Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate FGFR , Reactive Oxygen Species , 5-HT Receptor , Endogenous Metabolite
Ferulic acid sodium (Sodium ferulic), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular diseases and to prevent thrombosis.
T68022L Sulotroban potassium BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base) PPAR
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.
T68078 Gantofiban Integrin
Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.
T29215 Zifaxaban TY 602,TY602,TY-602 Factor Xa
Zifaxaban (TY-602) is an orally active, competitive and selective inhibitor of factor Xa (FXa) with an IC50 of 11.1 nM for human FXa.Zifaxaban has a very high affinity, more than 10,000-fold higher than that of other ser...
T6952 Prasugrel Hydrochloride LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl P2Y Receptor
Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.

Compounds

BPTU
T4132
Synonym: BMS-646786
Target: P2Y Receptor
NSC 405020
T1891
Synonym:
Target: MMP
UNC2881
T2629
Synonym:
Target: TAM Receptor
Toddalolactone
T4S0592
Synonym: (+)-Toddalolactone
Target: PAI-1
Sarpogrelate hydrochloride
T4978
Synonym: MCI-9042
Target: 5-HT Receptor
Kinetin
T2223
Synonym: 6-Furfuryladenine,N6-Furfuryladenine
Target: Others
Pipobroman
T4570
Synonym: Vercyte,A-8103,Amedel
Target: Others, DNA Alkylator/Crosslinker
SCH79797 dihydrochloride
T12870
Synonym:
Target: Apoptosis, Others, Protease-activated Receptor
Aspirin
T0005
Synonym: Acetylsalicylate,Acetylsalicylic Acid,ASA
Target: Mitophagy, Virus Protease, COX, Autophagy
Regrelor disodium
T34280
Synonym: INS-50589,INS50589,Regrelor sodium,Regrelor,INS 50589
Target: P2Y Receptor
Xemilofiban
T35161
Synonym: SC-54684A,SC54684A,SC 54684A
Target: Others
Octimibate
T24567
Synonym: Octimibato
Target: Prostaglandin Receptor
PCI-27483
T3469
Synonym: PCI27483
Target: Others
WAY-639228
T80792
Synonym:
Target: Others
Isbogrel
T27630
Synonym: CV4151,CV-4151,CV 4151
Target: Prostaglandin Receptor
Ferulic acid sodium
T2S0007
Synonym: Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate
Target: FGFR, Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite
Sulotroban potassium
T68022L
Synonym: BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base)
Target: PPAR
Gantofiban
T68078
Synonym:
Target: Integrin
Zifaxaban
T29215
Synonym: TY 602,TY602,TY-602
Target: Factor Xa
Prasugrel Hydrochloride
T6952
Synonym: LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl
Target: P2Y Receptor
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TargetMol