Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Zifaxaban (TY-602) is an orally active, competitive and selective inhibitor of factor Xa (FXa) with an IC50 of 11.1 nM for human FXa.Zifaxaban has a very high affinity, more than 10,000-fold higher than that of other serine proteases.Zifaxaban can be used to study arterial and venous thrombosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 350.00 | |
5 mg | In stock | $ 828.00 | |
10 mg | In stock | $ 1,130.00 | |
25 mg | In stock | $ 1,590.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,500.00 | |
500 mg | In stock | $ 4,900.00 |
Description | Zifaxaban (TY-602) is an orally active, competitive and selective inhibitor of factor Xa (FXa) with an IC50 of 11.1 nM for human FXa.Zifaxaban has a very high affinity, more than 10,000-fold higher than that of other serine proteases.Zifaxaban can be used to study arterial and venous thrombosis. |
Targets&IC50 | FXa (human):11.1 nM |
In vivo |
Zifaxaban (rat venous thrombosis model) strongly inhibits thrombosis with an ED50 value of 3.09 mg/kg, with optimal efficacy occurring 2 hours after administration.[1] Zifaxaban inhibits thrombosis in a dose-dependent manner in rat arteriovenous shunt thrombosis and carotid artery thrombosis models.[1] |
Synonyms | TY 602, TY602, TY-602 |
Molecular Weight | 429.88 |
Formula | C20H16ClN3O4S |
CAS No. | 1378266-98-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Zifaxaban 1378266-98-8 Metabolism Factor Xa TY 602 TY602 TY-602 inhibitor inhibit