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Search Results for " retinal "

20

Compounds

Cat No. Product Name Synonyms Targets
T5256 All-trans-retinal All trans-Retinal,Retinaldehyde,Vitamin A aldehyde Others , Endogenous Metabolite
All-trans-retinal (Vitamin A aldehyde) is a one of the major vitamin A metabolites in the retina. All-trans-RAL is regenerated to the visual chromophore, 11-cis-retinal in physiological conditions.
T38219 11-cis Retinal
11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to for...
T19169 9-cis-Retinal Others
9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to CRBP-I and CRBP-II (Kds: 8 nM and 5 nM). It expedites differentiation and ma...
T39280 Nitrofen Others
Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.
T12095 Monomethyl fumarate GPR , Drug Metabolite
Monomethyl fumarate is a potent agonist of GPR109A .
T2055 WS3 EGFR , IκB/IKK
WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.
T2026 CYM5442 S1P Receptor , LPL Receptor
CYM5442 is an S1P agonist, targeting to Sphingosine.
T21807 INCA-6 Triptycene-1,4-quinone Others
INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 inhibits of CN-NFAT signaling by targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site.
T5194 SPHINX31 Serine/threonin kinase
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
T29395 3-Diazirinophenylretinal
3-Diazirinophenylretinal is a bioactive chemical.
T34299 Retinaloxime trans-Retinaloxime
Retinaloxime is a retinoid.
T25829 Mopidamol RA233,RA 233,RA-233,Rapenton,OLX 102 PDE
Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimental diabetes.
T62858 HGPR91 antagonist 3 GPR
hGPR91 antagonist 3 is an orally active, potent, and selective hGPR91 antagonist. hGPR91 antagonist 3 is used to study hypertension, autoimmune diseases, and retinal angiogenesis. hGPR91 antagonist 3 has been shown to be...
T5913 Sulbutiamine Bisibuthiamine Antioxidant
Sulbutiamine (Bisibuthiamine) is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.
T30480 BiP inducer X BIX Apoptosis
BiP inducer X (BIX) is a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78 and an ER chaperone inducer. BiP inducer X prevents cell death in neurons and retinal cell lines.
T0685 Retinyl acetate Vitamin A acetate,Retinyl (Retinol) Acetate,Retinol acetate
Retinyl acetate (Vitamin A acetate) is a group of unsaturated nutritional hydrocarbons, that contains retinal, retinol, retinoic acid, and several provitamins A carotenoids, among which beta-carotene is the most importan...
T22282 Brr2-IN-3 Brr2 Inhibitor 9,Brr2 Inhibitor C9 Others
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).
T72662 NMDAR/TRPM4-IN-2 ERK , TRP/TRPV Channel , NMDAR , iGluR
NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprot...
T37081 HIOC
Selective TrkB receptor agonist. Protects neurons from excitotoxicity. Protects retinas from light-induced retinal degeneration (LIRD) in vivo. Blood brain barrier and blood-retinal barrier penetrant.
T13524 9-cis-β-Carotene Others
9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal. It inhibits photoreceptor degeneration and restores retinal function in vivo.
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TargetMol