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Retinyl acetate

Catalog No. T0685   CAS 127-47-9
Synonyms: Vitamin A acetate, Retinyl (Retinol) Acetate, Retinol acetate

Retinyl acetate (Vitamin A acetate) is a group of unsaturated nutritional hydrocarbons, that contains retinal, retinol, retinoic acid, and several provitamins A carotenoids, among which beta-carotene is the most important.

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Retinyl acetate Chemical Structure
Retinyl acetate, CAS 127-47-9
Pack Size Availability Price/USD Quantity
100 mg In stock $ 50.00
1 mL * 10 mM (in DMSO) In stock $ 33.00
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Purity: 90.23%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Retinyl acetate (Vitamin A acetate) is a group of unsaturated nutritional hydrocarbons, that contains retinal, retinol, retinoic acid, and several provitamins A carotenoids, among which beta-carotene is the most important.
In vitro Vitamin A deficiency impairs innate immunity by impeding normal regeneration of mucosal barriers damaged by infection, and by diminishing the function of neutrophils, macrophages, and natural killer cells. Vitamin A is also required for adaptive immunity and plays a role in the development of T both-helper (Th) cells and B-cells. Vitamin A deficiency diminishes antibody-mediated responses directed by Th2 cells, although some aspects of Th1-mediated immunity are also diminished. [1]
In vivo Vitamin A acetate (VAA) (fed on an otherwise conventional diet) responds to 105 semiallogeneic cells (a suboptimal dose) in a host-versus-graft (HvG) reaction in mice, whereas mice on a conventional diet do not. [2] Vitamin A acetate can bring a solid and long-lasting state of tolerance induced by the intravenous injection into newborn CBA mice of lymphoid cells from (CBA X C57BL/10ScSn) F1 hybrids to an end, the effect of which is to increase the proportion of the moiety of the T-cell population that produces IL-2. [3] Vitamin A acetate-supplemented diet develops a positive skin reaction to purified protein derivative of mycobacteria in High-dose Mycobacterium bovis-infected mice, and their spleen cells show an increased IL-2 production in vitro. [4]
Synonyms Vitamin A acetate, Retinyl (Retinol) Acetate, Retinol acetate
Molecular Weight 328.49
Formula C22H32O2
CAS No. 127-47-9

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 60 mg/mL (182.6 mM)

DMSO: 60 mg/mL (182.6 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

TargetMolReferences and Literature

1. Stephensen CB, et al. Annu Rev Nutr, 2001, 21, 167-192. 2. Malkovsky M, et al. Nature, 1983 Mar, 302(5906), 338-340. 3. Malkovsky M, et al. Proc Natl Acad Sci U S A, 1985, 82(2), 536-538. 4. Colizzi V, et al. Infect Immun, 1985, 48(2), 581-583.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Natural Product Library for HTS Anti-Cancer Active Compound Library Drug Repurposing Compound Library Natural Product Library NO PAINS Compound Library Bioactive Lipid Compound Library FDA-Approved & Pharmacopeia Drug Library Selected Plant-Sourced Compound Library

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Keywords

Retinyl acetate 127-47-9 Retinyl Vitamin A acetate Retinyl (Retinol) Acetate Inhibitor Vitamin A inhibit Retinol acetate Vitamin A Acetate Retinol Retinyl Acetate Retinol Acetate inhibitor

 

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