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Brr2-IN-3

🥰Excellent
Catalog No. T22282Cas No. 2104030-82-0
Alias Brr2 Inhibitor C9, Brr2 Inhibitor 9

Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).

Brr2-IN-3

Brr2-IN-3

🥰Excellent
Purity: 99.26%
Catalog No. T22282Alias Brr2 Inhibitor C9, Brr2 Inhibitor 9Cas No. 2104030-82-0
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).
Pack SizePriceAvailabilityQuantity
1 mg$46 In Stock
2 mg$63 In Stock
5 mg$98 In Stock
10 mg$173 In Stock
25 mg$323 In Stock
50 mg$467 In Stock
100 mg$653 In Stock
200 mg$879 In Stock
1 mL x 10 mM (in DMSO)$118 In Stock
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Purity:99.26%
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COA LCMS HPLC HNMR
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Product Introduction

Bioactivity
Description
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).
Targets&IC50
BRR2:1.3 μM (IC50)
AliasBrr2 Inhibitor C9, Brr2 Inhibitor 9
Chemical Properties
Molecular Weight444.51
FormulaC24H20N4O3S
Cas No.2104030-82-0
SmilesO=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2cncs2)c1
Relative Density.1.44 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 27.5 mg/mL (61.87 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2497 mL11.2483 mL22.4967 mL112.4834 mL
5 mM0.4499 mL2.2497 mL4.4993 mL22.4967 mL
10 mM0.2250 mL1.1248 mL2.2497 mL11.2483 mL
20 mM0.1125 mL0.5624 mL1.1248 mL5.6242 mL
50 mM0.0450 mL0.2250 mL0.4499 mL2.2497 mL

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Keywords

targetingspliceosomal RNA helicase Brr2selectivepotentInhibitorinhibithelicasedose-dependentBrr2-IN-3Brr-2-IN-3Brr2IN3Brr2 IN 3allosteric
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