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Brr2-IN-3

Catalog No. T22282 CAS 2104030-82-0

Synonyms: Brr2 Inhibitor 9, Brr2 Inhibitor C9

Brr2 inhibitor C9 is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).

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Brr2-IN-3, CAS 2104030-82-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 76.00
5 mg	In stock	$ 163.00
10 mg	In stock	$ 289.00
25 mg	In stock	$ 538.00
50 mg	In stock	$ 778.00
100 mg	In stock	$ 1,090.00
1 mL * 10 mM (in DMSO)	In stock	$ 197.00

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Purity: 99.12%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Brr2 inhibitor C9 is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).
Targets&IC50	Brr2:1.3 μM (IC50)

Synonyms	Brr2 Inhibitor 9, Brr2 Inhibitor C9
Molecular Weight	444.5
Formula	C24H20N4O3S
CAS No.	2104030-82-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 27.5 mg/mL (61.87 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compound Library NO PAINS Compound Library DNA Damage & Repair Compound Library Bioactive Compounds Library Max

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Brr2-IN-3 2104030-82-0 Others Inhibitor selective dose-dependent Brr2IN3 inhibit Brr2 Inhibitor 9 helicase Brr2 Inhibitor C9 Brr-2-IN-3 targeting potent allosteric Brr2 IN 3 inhibitor

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