Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CYM5442 is an S1P agonist, targeting to Sphingosine.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 157.00 | |
25 mg | In stock | $ 297.00 | |
50 mg | In stock | $ 559.00 | |
100 mg | In stock | $ 789.00 | |
500 mg | In stock | $ 1,660.00 |
Description | CYM5442 is an S1P agonist, targeting to Sphingosine. |
Targets&IC50 | Sphingosine 1-phosphate (S1P1) receptor:1.35 nM (EC50) |
Kinase Assay | HDAC activity is detected as described in the Colorimetric HDAC Activity Assay kit. Each reaction (100 μL) contains nuclear protein (50 μg) extract from leukaemia cells and HDAC substrate. To test the effect of HDACis, Chidamide (CS055) and MS-275 are added to the mixtures and incubated at 37°C for 1 h. The HDAC activities are measured by a microplate readers at 405 nm. The positive control (only nuclear extract and vehicle) is set as 100% and double-distilled water containing 10 μM Trichostatin A, a known strong HDACi, is used as a negative control and set as 0%[2]. |
Molecular Weight | 409.48 |
Formula | C23H27N3O4 |
CAS No. | 1094042-01-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Slightly soluble
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CYM5442 1094042-01-9 GPCR/G Protein S1P Receptor LPL Receptor retinal ubiquitination Lysophospholipid Receptor S1P1 CNS Inhibitor p42/p44 inhibit CYM 5442 endothelin-1 internalization CYM-5442 ganglion phosphorylation inhibitor