primary — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6793	BRD7552		Others
	BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.		Others
T12115	MSC2360844		PI3K
	MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).		PI3K
T8779	HBT1		GluR
	HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate...		GluR
T4277	Osilodrostat	LCI699	Glucocorticoid Receptor , Others , Hydroxylase
	Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM).		Glucocorticoid Receptor , Others , Hydroxylase
TD0101	AQC	6-Aminoquinolyl-N-hydroxysccinimidyl carbamate	Others
	AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent for the fluorescence detection of amino acid or protein sequence by HPLC. AQC reacts with primary and sec...		Others
T9149	2BAct	2B-Act,2B Act	PERK
	2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response		PERK
T3978	Linerixibat	GSK2330672,Iinerixibat	HBV
	Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.		HBV
T1684	Nitisinone	NTBC,SC0735,Nitisone	Others , Reactive Oxygen Species
	Nitisinone (SC0735)(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.		Others , Reactive Oxygen Species
T31964	Glycolithocholic acid	Lithocholic acid glycine conjugate,Lithocholylglycine	Others
	Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.		Others
T1882	Meisoindigo	N-Methylisoindigotin,Methylisoindigotin,Natura-α,Dian III	Apoptosis
	Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).		Apoptosis
T3184	Kevetrin hydrochloride	Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride	Mdm2 , p53
	Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.		Mdm2 , p53
T21510	PSI		Proteasome
	PSI is a proteasome inhibitor.		Proteasome
T19931	Gentisein	NSC 329491,NSC329491,NSC-329491	Serotonin Transporter
	Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2].		Serotonin Transporter
T2977	Vanillin acetate	Acetovanillin,Acetylvanillin,4-Formyl-2-methoxyphenyl acetate,4-Acetoxy-3-methoxybenzaldehyde	Others
	Acetylvanillin is a derivative of Vanillin, the primary component found in vanilla bean extract.		Others
T34914	Trabodenoson	INNO-8875,INO-8875,PJ875,PJ-875,INNO 8875,INNO8875,PJ 875	Adenosine Receptor
	Trabodenoson (INO-8875) is a selective and potent adenosine A1 receptor agonist, an adenosine analog, for the study of primary open-angle glaucoma.		Adenosine Receptor
T25006	AGI-14100	AGI 14100	Dehydrogenase
	AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.		Dehydrogenase
T77621	Z16078526		p38 MAPK , Mitochondrial Metabolism
	Z16078526 enhances thermogenesis in mice by inducing endogenous Ucp1 expression, promoting p38 MAPK phosphorylation, and stimulating lipolysis in primary mouse brown adipocytes. Additionally, it activates thermogenic gen...		p38 MAPK , Mitochondrial Metabolism
T24865	Tenivastatin	L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid	ROS , HMG-CoA Reductase
	Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor that inhibits the production of reactive oxygen species (ROS) and can be used in the study of primary hyperlipidemia.		ROS , HMG-CoA Reductase
T4S0779	D-tetrahydropalmatine		Others , Dopamine Receptor
	D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability re...		Others , Dopamine Receptor
T18902	6-FAM	6-Carboxyfluorescein	Others
	6-Carboxyfluorescein (6-FAM) contains a carboxylic acid functional group, facilitating reactions with primary amines through carbodiimide activation.		Others