Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 80.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 318.00 | |
25 mg | In stock | $ 622.00 | |
50 mg | In stock | $ 997.00 | |
100 mg | In stock | $ 1,580.00 | |
500 mg | In stock | $ 3,160.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 229.00 |
Description | MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM). |
Targets&IC50 | PI3Kδ:145 nM |
In vitro | MSC2360844 inhibits B cell proliferation in a concentration-dependent manner with an IC50 of 48 nM. MSC2360844 blocks BCR- and TCR-mediated responses in lymphocytes and TLR-induced IFNα by pDC in human primary cells[1]. |
In vivo | in a murine SLE model,MSC2360844 ameliorates disease manifestations [1]. |
Molecular Weight | 526.58 |
Formula | C26H27FN4O5S |
CAS No. | 1305267-37-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (170.91 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MSC2360844 1305267-37-1 PI3K/Akt/mTOR signaling PI3K Phosphoinositide 3-kinase MSC 2360844 cells SLE-prone primary Inhibitor functions inhibit proliferation MSC-2360844 inhibitor