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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2466 | Platelet factor 4 (59-70) | PF4 (59-70) | |
Platelet factor 4 (59-70) elicits human neutrophil & monocyte chemotaxis. | |||
TP1667 | Platelet Factor 4 (58-70), human | ||
Platelet Factor 4 (58-70), human is a polypeptide based on the 58-70 amino acid sequence of Platelet Factor 4 (pf-4) residues. | |||
TP2198 | Platelet Membrane Glycoprotein IIB Peptide (296-306) | Others | |
GPllb is composed of a 125 Kd heavy chain that is disulfide-linked to a 23 Kd light chain. Hydropathicity analysis of the cDNA sequence indicates that GPllb is anchored to the platelet through a single transmembrane doma... | |||
T9030 | SU4984 | FGFR , IGF-1R , PDGFR | |
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1). | |||
T5036 | Cangrelor tetrasodium | GPR , P2Y Receptor | |
Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects. | |||
TN2085 | Piperlonguminine | Anti-infection , Antibacterial , Antifungal | |
Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities.Piperl... | |||
T6091 | CP-673451 | VEGFR , PDGFR , c-Kit | |
CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than other angiogenic receptors. | |||
T6S0139 | Neobavaisoflavone | Apoptosis , DNA/RNA Synthesis | |
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... | |||
T2734 | Sennoside B | PDGFR | |
Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation. | |||
T14137 | AG 1295 | PDGFR | |
AG 1295, a selective inhibitor of platelet-derived growth factor receptor (PDGFR) tyrosine-kinase, effectively halts PDGFR autophosphorylation without impacting the autophosphorylation of the EGF receptor[1][2][3][4]. | |||
T3781 | Jujuboside B | Others | |
Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, and also exhibits superior protection on the thromboembolic model. | |||
T3S1591 | Notoginsenoside Fc | Others , Autophagy | |
1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect. | |||
T6594 | MNS | Syk , Src , p97 | |
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively. | |||
T1265 | Amrinone | Inamrinone,Inocor,Wincoram | TNF , PDE |
Amrinone (Inocor) is a positive inotropic cardiotonic (cardiotonic agent) with vasodilator properties, phosphodiesterase 3 inhibitory activity. | |||
T5460 | Mofezolac | COX | |
Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000 | |||
T11339 | Furegrelate sodium | U-63557A | PPAR |
Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synthase in human platelet microsomes with an IC50 of 15 nM. | |||
T2629 | UNC2881 | TAM Receptor | |
UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively. | |||
T16975 | TAK-593 | VEGFR , PDGFR | |
TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGRα, and PDFGRβ, respectively). | |||
T26019 | R59949 | R-59949,R 59949 | Others , PKC |
R59949 is used as a Diacylglycerol kinase (DGK) inhibitor. | |||
T15031 | CYM50260 | Others , LPL Receptor | |
CYM50260 is a potent and exquisitely selective agonist of sphingosine-1-phosphate 4 receptor (S1P4-R, EC50= nM) with no activity against S1P1-R, S1P2-R, S1P3-R and S1P5-R. |