neuroprotective — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8588	Buramate		Antibacterial
	Buramate is an antipsychotic and anticonvulsant.		Antibacterial
TN1076	Oleonuezhenide		Others
	Oleonuezhenide is a natural product from Chinese formula Ligustrum lucidum, exerts neuroprotective effects and also considered as treatment of osteoporosis.		Others
TMS1743	Salvigenin		MAO , Autophagy , ROS Kinase
	Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.		MAO , Autophagy , ROS Kinase
T6S2227	Spinosin	Flavoayamenin	Others
	1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato...		Others
TN1772	Isoastilbin		Anti-infection , Tyrosinase , Antibacterial
	Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an...		Anti-infection , Tyrosinase , Antibacterial
T1880	P7C3		Others
	The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, be...		Others
T3464	PHCCC	(-) PHCCC	GluR
	PHCCC ((-) PHCCC) is a Group I metabotropic glutamate receptor antagonist and a positive allosteric modulator of mGluR4. It also is a potent to antagonism for mGluR2 and mGluR8.		GluR
T3236	Solanesol	Betulanonaprenol,Nonaisoprenol	Others , Endogenous Metabolite , Antibacterial
	Solanesol (Betulanonaprenol) is a phytochemical present in tobacco leaf. Starting material for synthesis of co-enzyme Q10. Exhibits antiulcer activity.		Others , Endogenous Metabolite , Antibacterial
T3769	Tenuifolin		Others , Beta-Secretase , AChE
	Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.		Others , Beta-Secretase , AChE
T21687	Conoidin A		Parasite
	Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation ...		Parasite
T8381	Amodiaquine		Others , Histone Methyltransferase , Parasite
	Amodiaquine is a synthetic aminoquinoline, used to treat malaria.		Others , Histone Methyltransferase , Parasite
TN2085	Piperlonguminine		Anti-infection , Antibacterial , Antifungal
	Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities.Piperl...		Anti-infection , Antibacterial , Antifungal
T3S0195	Nootkatone		AMPK
	1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent obesity and improve physical performance through AMPK activa...		AMPK
T2423	P7C3-A20		Others
	P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity.		Others
T2343	AS601245		JNK
	AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.		JNK
T8849	PF-9601N		MAO
	PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.		MAO
T29123	VU0152099	VU 0152099,VU-0152099	AChR
	VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).		AChR
TN2082	Pinostrobin		Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF
	Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress...		Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF
T12095	Monomethyl fumarate		GPR , Drug Metabolite
	Monomethyl fumarate is a potent agonist of GPR109A .		GPR , Drug Metabolite
T6S0721	Orientin	Lutexin,Luteolin-8-glucoside	Others
	1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...		Others