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Spinosin

Catalog No. T6S2227   CAS 72063-39-9
Synonyms: Flavoayamenin

1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas.

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Spinosin Chemical Structure
Spinosin, CAS 72063-39-9
Pack Size Availability Price/USD Quantity
20 mg In stock $ 90.00
1 mL * 10 mM (in DMSO) In stock $ 70.00
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Purity: 98.68%
Purity: 98.16%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammatory effects of Spinosin. 2. Spinosin exerts anxiolytic-like effects, and its mechanism of action appears to be modulated by GABAA and 5-HT1A receptors. 3. There was a wide brain regional tissue distribution of Spinosin. The concentrations of Spinosin in corpus striatum and hippocampus were higher than that in other areas.
Source
Synonyms Flavoayamenin
Molecular Weight 608.54
Formula C28H32O15
CAS No. 72063-39-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: Soluble

DMSO: 91 mg/mL(149.5 mM)

Pyridine, Methanol, etc.: Soluble

TargetMolReferences and Literature

1. Jung I H , Lee H E , Park S J , et al. Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice[J]. Pharmacology Biochemistry and Behavior, 2014, 120:88-94.

Related compound libraries

This product is contained In the following compound libraries:
Traditional Chinese Medicine Monomer Library Immunology/Inflammation Compound Library Anti-Aging Compound Library Natural Product Library Anti-COVID-19 Traditional Chinese Medicine Compound Library NO PAINS Compound Library Natural Product Library for HTS Chinese Pharmacopoeia Natural Product Library Food as Medicine Compound Library Anti-Fibrosis Compound Library

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Keywords

Spinosin 72063-39-9 Others Inhibitor neuroprotective Flavoayamenin inhibit Aβ1-42 inhibitor

 

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