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Search Results for " musculoskeletal "

20

Compounds

Cat No. Product Name Synonyms Targets
T7061 Duloxetine Serotonin Transporter
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.
T1409 Methocarbamol Lumirelax,Metocarbamol,AHR 85,Robaxin Sodium Channel , Carbonic Anhydrase
Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful musc...
T1471 Duloxetine hydrochloride Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i...
T27209 Droxicam Droxicamum Others
Droxicam (Droxicamum) is a non-steroidal anti-inflammatory compound and can be used for research on the relief of inflammation and pain in musculoskeletal disorders.
T34385 Ronacaleret HCl SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689 CaSR
Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.
T33876L1 Panomifene TFA Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA Estrogen/progestogen Receptor
Panomifene TFA(GYKl13504 TFA) is a small molecule antagonist of ERs with anticancer activity that can be used to study breast cancer and musculoskeletal diseases.
T1610 Metaxalone Skelaxin,Methaxalonum,Zorane,NSC170959,AHR438 Others
Metaxalone (Methaxalonum) (marketed by King Pharmaceuticals under the brand name Skelaxin ) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions.
T28453L Propiram fumarate HCl Propiram fumarate HCl(15686-91-6 Free base) Opioid Receptor
Propiram fumarate HClis an orally available Opioid receptors agonist with analgesic activity for the study of musculoskeletal pain.
T24755 Salnacedin G-201,SCY,G-201,G201,SCY,G 201 Others
Salnacedin (G-201) is a small molecule compound used in the treatment of immune system disorders, skin and musculoskeletal disorders, and can be used in studies of acne vulgaris, dermatitis and psoriasis.
T72023 JB002 Myosin
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
T15358 Funapide TV 45070,XEN402 Sodium Channel
Funapide (TV 45070) is a potent Sodium Channel Nav1.7 inhibitor with potential anti-inflammatory activity for the treatment of erythema gangrenosum, musculoskeletal pain, knee osteoarthritis, and postherpetic nerves.
T29663 ADL-5747 ADL-5747 (free base),ADL5747,ADL-5747 free base Opioid Receptor
ADL-5747 (ADL-5747 (free base)) (free base) is a delta opioid receptor agonist used in the treatment of neurological disorders, skin and musculoskeletal disorders, and may be used in the study of postherpetic neuralgia, ...
T0858 Flufenamic acid Arlef,Nichisedan,Achless Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.
T68126 Pemedolac Dexpemedolac COX
Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.
T7725 Albaconazole W 0027,UR-9825,UR9825,W-0027 P450 , Antifungal
Albaconazole (W-0027) is a small molecule fungal cytochrome P450 family member 51 (fungal CYP51A1) inhibitor. It is used in the treatment of fungal infections, skin and musculoskeletal disorders, and can be used in the s...
T0855 (R)-Naproxen COX
(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis...
T68108L Moxilubant HCl Moxilubant hcl(146978-48-5 Free base) LTR
Moxilubant HCl is a small molecule leukotriene B4 receptor 1 (LTB4R) antagonist for the treatment of immune system disorders, skin and musculoskeletal disorders, and may be used in studies of psoriasis and rheumatoid art...
T41303 Isoflupredone Delta-Fluorocortisone,Isoflupredona,Isoflupredonum,9-Fluoroprednisolone Others
Isoflupredone (Isoflupredonum) is a synthetic corticosteroid that acts in vivo by binding to glucocorticoid and corticosteroid receptors in animals (such as horses) to inhibit inflammatory cells and inhibit the expressio...
T67385 Neratinib maleate HKI-272 maleate EGFR , HER
Neratinib maleate (HKI-272 maleate) is an irreversible, orally active and highly selective inhibitor of HER2 and EGFR with IC50 values of 59 nM and 92 nM, respectively.Neratinib maleate has antitumor activity and can be ...
T67952 JB062 Myosin
JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It se...

Compounds

Duloxetine
T7061
Synonym:
Target: Serotonin Transporter
Methocarbamol
T1409
Synonym: Lumirelax,Metocarbamol,AHR 85,Robaxin
Target: Sodium Channel, Carbonic Anhydrase
Duloxetine hydrochloride
T1471
Synonym: Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
Droxicam
T27209
Synonym: Droxicamum
Target: Others
Ronacaleret HCl
T34385
Synonym: SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689
Target: CaSR
Panomifene TFA
T33876L1
Synonym: Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA
Target: Estrogen/progestogen Receptor
Metaxalone
T1610
Synonym: Skelaxin,Methaxalonum,Zorane,NSC170959,AHR438
Target: Others
Propiram fumarate HCl
T28453L
Synonym: Propiram fumarate HCl(15686-91-6 Free base)
Target: Opioid Receptor
Salnacedin
T24755
Synonym: G-201,SCY,G-201,G201,SCY,G 201
Target: Others
JB002
T72023
Synonym:
Target: Myosin
Funapide
T15358
Synonym: TV 45070,XEN402
Target: Sodium Channel
ADL-5747
T29663
Synonym: ADL-5747 (free base),ADL5747,ADL-5747 free base
Target: Opioid Receptor
Flufenamic acid
T0858
Synonym: Arlef,Nichisedan,Achless
Target: Potassium Channel, Calcium Channel, Chloride channel, COX, AMPK, Parasite
Pemedolac
T68126
Synonym: Dexpemedolac
Target: COX
Albaconazole
T7725
Synonym: W 0027,UR-9825,UR9825,W-0027
Target: P450, Antifungal
(R)-Naproxen
T0855
Synonym:
Target: COX
Moxilubant HCl
T68108L
Synonym: Moxilubant hcl(146978-48-5 Free base)
Target: LTR
Isoflupredone
T41303
Synonym: Delta-Fluorocortisone,Isoflupredona,Isoflupredonum,9-Fluoroprednisolone
Target: Others
Neratinib maleate
T67385
Synonym: HKI-272 maleate
Target: EGFR, HER
JB062
T67952
Synonym:
Target: Myosin
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TargetMol