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20

Compounds

Cat No. Product Name Synonyms Targets
T40130 Nur77 modulator 1 Nur77 modulator 1 Others
Nur77 modulator 1 is a good Nur77 binder (KD = 3.58 μM). Nur77 modulator 1 up-regulates Nur77 expression, mediates sub-cellular localization of Nur77, induces Nur77-dependent ER stress and autophagy, and results in cell ...
T21083 TFIIH Modulator-19 TFIIH Modulator19,TFIIH Modulator 19 Others
TFIIH Modulator-19 induces the dimerization of trichothiodystrophy group A protein to modulate TFIIH transcriptional activity.
T40997 GLP-1R modulator C16 GLP-1R modulator C16 Glucagon Receptor
GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.
T60063 Fluorogen binding modulator-1 Fluorogen binding modulator-1 Others
Fluorogen binding modulator-1 (Fluorogen binding modulator-1) is a nonfluorescent inhibitors of Fluorogen–Fluorogen Activating Protein Binding Pairn.
T40279 GLP-1R modulator L7-028 GLP-1R modulator L7-028 cAMP , Glucagon Receptor
GLP-1R modulator L7-028 is a variant modulator that enhances affinity for GLP-1 and cAMP signaling.
T12821 S1PR1 modulator 1 LPL Receptor
S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.
T10696 CB2 modulator 1 Cannabinoid Receptor
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.
T10168 5-HT1A modulator 1 5-HT1Amodulator1 Phospholipase , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).
T12922 Sirtuin modulator 1 SRT3025 Hydrochloride Sirtuin
Sirtuin modulator 1 (SRT3025 Hydrochloride) is a modulator of SIRT1 with EC1.5 of < 1 μM.
T37734 AMPA receptor modulator-2 GluR
AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AM...
T67832 ALDH2 modulator 1 Dehydrogenase
ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
T11458 GPR40/FFAR1 modulator 1 GPR
GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator.
T67745 CB2R/FAAH modulator-2 Cannabinoid Receptor , FAAH
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, an...
T8824 CRBN modulator-1 WUN29654 Others , Ligand for E3 Ligase
CRBN modulator-1 (WUN29654) is a Thalidomide analog and CRBN modulator,has an IC50 of 3.5 μM and a Ki of 0.98 μM.
T67884 β-catenin modulator IIa-661 Wnt/beta-catenin
β-catenin modulator IIa-661 is a small molecule inhibitor of the Wnt pathway with antitumour activity.
T10101 Calcium channel-modulator-1 Others , Calcium Channel
Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.
T9999 Sirtuin modulator 2 N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide Others , Sirtuin
Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.
T36526 IL-17 modulator 4 Interleukin
IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17.
T67747 CB2R/FAAH modulator-3 Cannabinoid Receptor , FAAH
CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 20.1 and 67.6 nM for CB2R and CB1R, respectively, and the ...
T10307 AMPA receptor modulator-1 iGluR
AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.

Compounds

Nur77 modulator 1
T40130
Synonym: Nur77 modulator 1
Target: Others
TFIIH Modulator-19
T21083
Synonym: TFIIH Modulator19,TFIIH Modulator 19
Target: Others
GLP-1R modulator C16
T40997
Synonym: GLP-1R modulator C16
Target: Glucagon Receptor
Fluorogen binding modulator-1
T60063
Synonym: Fluorogen binding modulator-1
Target: Others
GLP-1R modulator L7-028
T40279
Synonym: GLP-1R modulator L7-028
Target: cAMP, Glucagon Receptor
S1PR1 modulator 1
T12821
Synonym:
Target: LPL Receptor
CB2 modulator 1
T10696
Synonym:
Target: Cannabinoid Receptor
5-HT1A modulator 1
T10168
Synonym: 5-HT1Amodulator1
Target: Phospholipase, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Sirtuin modulator 1
T12922
Synonym: SRT3025 Hydrochloride
Target: Sirtuin
AMPA receptor modulator-2
T37734
Synonym:
Target: GluR
ALDH2 modulator 1
T67832
Synonym:
Target: Dehydrogenase
GPR40/FFAR1 modulator 1
T11458
Synonym:
Target: GPR
CB2R/FAAH modulator-2
T67745
Synonym:
Target: Cannabinoid Receptor, FAAH
CRBN modulator-1
T8824
Synonym: WUN29654
Target: Others, Ligand for E3 Ligase
β-catenin modulator IIa-661
T67884
Synonym:
Target: Wnt/beta-catenin
Calcium channel-modulator-1
T10101
Synonym:
Target: Others, Calcium Channel
Sirtuin modulator 2
T9999
Synonym: N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide
Target: Others, Sirtuin
IL-17 modulator 4
T36526
Synonym:
Target: Interleukin
CB2R/FAAH modulator-3
T67747
Synonym:
Target: Cannabinoid Receptor, FAAH
AMPA receptor modulator-1
T10307
Synonym:
Target: iGluR
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TargetMol