Powder: -20°C for 3 years
In solvent: -80°C for 2 years
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
Description | CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection. |
In vitro | CB2R/FAAH modulator-2 (compound 26)(10 μ M) can reduce the production of pro-inflammatory cytokine TNF α、 IFN- γ、 IL-1 β and IL6 in unstimulated monocytes and macrophages[1]. |
Molecular Weight | 367.52 |
Formula | C24H33NO2 |
CAS No. | 2876918-68-0 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 3.68 mg/mL (10 mM), Need ultrasound
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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CB2R/FAAH modulator-2 2876918-68-0 GPCR/G Protein Metabolism Neuroscience FAAH Cannabinoid Receptor CB2R/FAAH modulator2 Inhibitor inhibitor inhibit