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CRBN modulator-1

Catalog No. T8824 CAS 2407829-65-4

Synonyms: WUN29654

CRBN modulator-1 (WUN29654) is a Thalidomide analog and CRBN modulator,has an IC50 of 3.5 μM and a Ki of 0.98 μM.

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CRBN modulator-1, CAS 2407829-65-4

Pack Size	Availability	Price/USD
1 mg	In stock	$ 56.00
5 mg	In stock	$ 122.00
10 mg	In stock	$ 197.00
25 mg	In stock	$ 372.00
50 mg	In stock	$ 556.00
100 mg	In stock	$ 783.00
500 mg	In stock	$ 1,650.00
1 mL * 10 mM (in DMSO)	In stock	$ 133.00

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Purity: 99.36%

Purity: 99.24%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

CRBN modulator-1 (WUN29654) is a Thalidomide analog and CRBN modulator,has an IC50 of 3.5 μM and a Ki of 0.98 μM.

Synonyms	WUN29654
Molecular Weight	324.29
Formula	C17H12N2O5
CAS No.	2407829-65-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

References and Literature

1. Nathanael Gray, et al. New crbn modulators. WO2020006262A1.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library NO PAINS Compound Library Bioactive Compounds Library Max

Related Products

Related compounds with same targets

VH032 (S,R,S)-AHPC-Me hydrochloride (S,R,S)-AHPC-Me-C10-NH2 hydrochloride VL285 Pomalidomide-PEG4-Ph-NH2 Lenalidomide-OH HaloPROTAC3 Pomalidomide-C2-NH2 hydrochloride

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CRBN modulator-1 2407829-65-4 Others PROTAC Ligand for E3 Ligase CRBN modulator1 inhibit CRBN modulator 1 Ligands for E3 Ligase WUN 29654 E3 ligase-recruiting Moiety WUN29654 WUN-29654 Inhibitor inhibitor

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