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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23027 | MRT-10 | Hedgehog/Smoothened | |
MRT-10 is a Smoothened (Smo) receptor antagonist. | |||
T6S1027 | Tussilagone | Others | |
1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co... | |||
T5826 | Eupalinolide A | HSP | |
Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines. | |||
T3804 | Neomangiferin | Mangiferin 7-glucoside | Phosphatase |
Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar... | |||
T5491 | GSK3179106 | c-RET | |
GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM | |||
TP1889 | MCL0020 | MCL 0020 | Melanocortin Receptor |
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no e... | |||
TQ0105 | CAY10650 | Phospholipase | |
CAY10650 is an effective inhibitor of cytosolic phospholipase A2α (cPLA2α, IC50: 12 nM). | |||
T23312 | SB 204741 | 5-HT Receptor | |
SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1. | |||
T9266 | Fatostatin | Lipid , Fatty Acid Synthase | |
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. | |||
T4S0537 | Neoline | Bullatine B | Others |
Neoline (Bullatine B) shows analgesic/anti-inflammatory properties. | |||
T9614 | MERS-CoV-IN-1 | SARS-CoV | |
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS). | |||
T7954 | YM976 | PDE | |
YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM) | |||
T1997 | JNJ-31020028 | JNJ 31020028 | Neuropeptide Y Receptor |
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors. | |||
T16481 | PF-04995274 | 5-HT Receptor | |
PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease. PF-04995274 has a... | |||
T21807 | INCA-6 | Triptycene-1,4-quinone | Others |
INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 inhibits of CN-NFAT signaling by targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site. | |||
T8235 | L-732138 | Neurokinin receptor | |
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM) | |||
T8496 | MAZ51 | Apoptosis , VEGFR | |
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor. | |||
T1893 | Parmodulin 2 | ML 161 | Protease-activated Receptor |
Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb... | |||
T2040 | OAC1 | BAS 00287861 | OCT |
OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process. | |||
T0839 | Ketoprofen | RP-19583 | Apoptosis , COX , MRP |
Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenas... |