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20

Compounds

Cat No. Product Name Synonyms Targets
T23027 MRT-10 Hedgehog/Smoothened
MRT-10 is a Smoothened (Smo) receptor antagonist.
T6S1027 Tussilagone Others
1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co...
T5826 Eupalinolide A HSP
Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.
T3804 Neomangiferin Mangiferin 7-glucoside Phosphatase
Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar...
T5491 GSK3179106 c-RET
GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM
TP1889 MCL0020 MCL 0020 Melanocortin Receptor
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no e...
TQ0105 CAY10650 Phospholipase
CAY10650 is an effective inhibitor of cytosolic phospholipase A2α (cPLA2α, IC50: 12 nM).
T23312 SB 204741 5-HT Receptor
SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.
T9266 Fatostatin Lipid , Fatty Acid Synthase
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs.
T4S0537 Neoline Bullatine B Others
Neoline (Bullatine B) shows analgesic/anti-inflammatory properties.
T9614 MERS-CoV-IN-1 SARS-CoV
MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS).
T7954 YM976 PDE
YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)
T1997 JNJ-31020028 JNJ 31020028 Neuropeptide Y Receptor
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
T16481 PF-04995274 5-HT Receptor
PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease. PF-04995274 has a...
T21807 INCA-6 Triptycene-1,4-quinone Others
INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 inhibits of CN-NFAT signaling by targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site.
T8235 L-732138 Neurokinin receptor
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)
T8496 MAZ51 Apoptosis , VEGFR
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
T1893 Parmodulin 2 ML 161 Protease-activated Receptor
Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...
T2040 OAC1 BAS 00287861 OCT
OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.
T0839 Ketoprofen RP-19583 Apoptosis , COX , MRP
Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenas...
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